Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02507284 · ClinicalTrials.gov registry record · Phase 2

Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease

A Phase 2 study, sponsored by Azevan Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
106
Enrollment target

NCT02507284: Completed Phase 2 study, sponsored by Azevan Pharmaceuticals.

NCT02507284 is a Phase 2 study that has completed, run by Azevan Pharmaceuticals. The registered enrollment target is 106 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT02507284, a Phase 2 study, has completed, sponsored by Azevan Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
106 participants
Enrollment target

Study Summary

This study evaluates the tolerability, safety and activity of SRX246 in the treatment of irritability in patients with Huntington's disease. Two-thirds of all participants will receive SRX246, while the other third will receive a placebo.

Primary Outcome

The primary endpoint, tolerability of SRX246, was assessed by the number of completers in each group.

Interventions

  • DRUG Placebo
  • DRUG SRX246

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2016-05-10
Est. Completion 2018-12-21
Phase Phase 2
Azevan Pharmaceuticals

8 total trials

What the finished NCT02507284 record still lists

NCT02507284 is an interventional study that assigns participants to a tested intervention. The registered 106 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (20% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02507284 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02507284 about?

NCT02507284 is a clinical study titled "Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease". This study evaluates the tolerability, safety and activity of SRX246 in the treatment of irritability in patients with Huntington's disease. Two-thirds of all participants will receive SRX246, while the other third will receive a placebo.

What is the current status of trial NCT02507284?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 106 participants. The study started on 2016-05-10. Estimated completion is 2018-12-21.

What interventions are being tested in trial NCT02507284?

The interventions under investigation include: Placebo (DRUG), SRX246 (DRUG).

Who is sponsoring clinical trial NCT02507284?

This trial is sponsored by Azevan Pharmaceuticals, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02507284's enrollment target sits among peer trials

106 648th of 2000 higher than 1,351 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03181048 · 106 participants · NA

    Clinical Trial of Concomitant Hip Arthroscopy During PAO

  • NCT04682158 · 106 participants · Phase 2

    Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma

  • NCT04724018 · 106 participants · Phase 1

    Sacituzumab Govitecan Plus EV in Metastatic UC

  • NCT04798274 · 106 participants · NA

    Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02507284, the US trial registry maintained by the National Library of Medicine. NCT02507284 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.