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NCT02502786 · ClinicalTrials.gov registry record · Phase 2

Humanized Monoclonal Antibody 3F8 (Hu3F8) With Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in the Treatment of Recurrent Osteosarcoma

A Phase 2 study of Recurrent Osteosarcoma, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Phase 2
Development phase
46
Enrollment target
3
Study locations

NCT02502786: Active Phase 2 study of Recurrent Osteosarcoma, sponsored by Memorial Sloan Kettering Cancer Center.

NCT02502786 is a Phase 2 study of Recurrent Osteosarcoma that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 46 participants, below the 63-participant average among 13 other Recurrent Osteosarcoma trials with a reported enrollment target (27% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02502786, a Phase 2 study of Recurrent Osteosarcoma, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
46 participants
Enrollment target
3
Study locations

Study Summary

The purpose of this study is to find out what effect an antibody called Humanized 3F8 (Hu3F8) and a drug called GM-CSF have on the patient and whether it can keep the patient in remission longer and/or prevent recurrence of the disease.

Primary Outcome

EFS is defined as the time from surgery to relapse or death from any cause, recurrence of tumor or second malignancy.

Conditions Studied

Interventions

  • DRUG GM-CSF
  • BIOLOGICAL humanized anti-GD2 antibody

Study Locations (3)

California

  • Children's Hospital of Los Angeles (Data Collection Only) - Los Angeles

New York

  • Memorial Sloan Kettering Cancer Center - New York

Texas

  • MD ANDERSON CANCER CENTER (Data Collection Only) - Houston

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2015-07
Est. Completion 2026-07
Phase Phase 2
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the registry record for NCT02502786 still lists

NCT02502786 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 63-participant average among 13 other Recurrent Osteosarcoma trials with a reported enrollment target (27% lower).

The record links to 1 condition, with Recurrent Osteosarcoma appearing as the primary indexed condition, and to 2 interventions - of which GM-CSF is the first listed.

NCT02502786 reports a single indexed study location in California, New York, Texas.

Frequently Asked Questions

What is clinical trial NCT02502786 about?

NCT02502786 is a clinical study titled "Humanized Monoclonal Antibody 3F8 (Hu3F8) With Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in the Treatment of Recurrent Osteosarcoma". The purpose of this study is to find out what effect an antibody called Humanized 3F8 (Hu3F8) and a drug called GM-CSF have on the patient and whether it can keep the patient in remission longer and/or prevent recurrence of the disease.

What is the current status of trial NCT02502786?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 2015-07. Estimated completion is 2026-07.

What conditions does trial NCT02502786 study?

This clinical trial studies the following conditions: Recurrent Osteosarcoma.

What interventions are being tested in trial NCT02502786?

The interventions under investigation include: GM-CSF (DRUG), humanized anti-GD2 antibody (BIOLOGICAL).

Who is sponsoring clinical trial NCT02502786?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02502786 being conducted?

This trial has 3 study locations across California, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Recurrent Osteosarcoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02502786's enrollment target sits among peer trials

46 6th of 13 higher than 8 of 13 other Recurrent Osteosarcoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Recurrent Osteosarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02502786, the US trial registry maintained by the National Library of Medicine. NCT02502786 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.