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NCT02500719 · ClinicalTrials.gov registry record · NA

Real-time fMRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD

A NA study, sponsored by University of Arkansas.

Completed
Registry status
NA
Development phase
30
Enrollment target

NCT02500719: Completed NA study, sponsored by University of Arkansas.

NCT02500719 is a NA study that has completed, run by University of Arkansas. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02500719, a NA study, has completed, sponsored by University of Arkansas.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

The purpose of the current study is to develop a better understanding of the brain mechanisms involved in psychological treatments for posttraumatic stress disorder (PTSD). This project will build on past research using script-driven imagery in our lab by investigating brain activity in areas activated during exposure to trauma-related cues. This project will also develop new knowledge concerning volitional control of those areas. The ultimate goal of this study is a better understanding of whether volitional control of these brain areas will improve therapeutic outcomes. This process will first be piloted in a sample of healthy controls. This will allow investigators to refine the methodology prior to recruiting a sample with PTSD.

Primary Outcome

Support vector machine decodings of functional MRI data acquired during volitional engagement or disengagement of emotional arousal. Each decoding represents the Euclidean distance and direction (either positive or negative) of the functional MRI data volume with respect to the patient's support vector machine decision hyperplane. Positive distances denote engagement of emotional arousal and negative distances denote disengagement of emotion arousal. Distance represents the magnitude of volition

Interventions

  • DEVICE Computational Model - Real-time Support Vector Machine

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2015-08-15
Est. Completion 2019-04
Phase NA
University of Arkansas

318 total trials

What the finished NCT02500719 record still lists

NCT02500719 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Computational Model - Real-time Support Vector Machine is the first listed.

NCT02500719 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02500719 about?

NCT02500719 is a clinical study titled "Real-time fMRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD". The purpose of the current study is to develop a better understanding of the brain mechanisms involved in psychological treatments for posttraumatic stress disorder (PTSD). This project will build on past research using script-driven imagery in our lab by investigating brain activity in areas activa...

What is the current status of trial NCT02500719?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2015-08-15. Estimated completion is 2019-04.

What interventions are being tested in trial NCT02500719?

The interventions under investigation include: Computational Model - Real-time Support Vector Machine (DEVICE).

Who is sponsoring clinical trial NCT02500719?

This trial is sponsored by University of Arkansas, which has 318 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02500719's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02500719, the US trial registry maintained by the National Library of Medicine. NCT02500719 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.