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NCT02494635 · ClinicalTrials.gov registry record
Ultrasound and Biomarker Tests in Predicting Cancer Aggressiveness in Tissue Samples of Patients With Bladder Cancer
A clinical trial, sponsored by University of Southern California.
- Terminated
- Registry status
- 4
- Enrollment target
NCT02494635: Clinical Trial study, sponsored by University of Southern California.
NCT02494635 is a clinical trial that was terminated before completion, run by University of Southern California. The registered enrollment target is 4 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02494635 was terminated before completion, sponsored by University of Southern California.
- TERMINATED
- Registry status
- 4 participants
- Enrollment target
Study Summary
This research trial studies two types of tests, an ultrasound test and a biomarker test, to see how well they predict how aggressive (invasive) bladder cancer is in samples from patients with bladder cancer. The aggressiveness of a tumor means how likely it is to invade the body and spread. The ultrasound test uses a fluorescent dye and stimulates cells under a microscope to see how they respond. This may allow doctors to predict how likely the cancer cells are to spread in the body. The biomarker test uses laboratory testing of samples from patients to study genes and other molecules that may predict the cancer invasiveness. Comparing two different ways of predicting cancer aggressiveness may help doctors identify how well they work, and may eventually allow doctors to predict aggressiveness without needing to take a biopsy.
Primary Outcome
Data will be post-processed to determine the level of ultrasound-induced calcium response at each stimulus amplitude. Cell locations will be identified with CellProfiler image analysis software and used to extract the raw fluorescence intensities for each cell. CRI will be plotted against stimulus amplitude, a sigmoid will be fit to the curve, and threshold will be defined as the amplitude that yielded a 50% response.
Interventions
- OTHER Laboratory Biomarker Analysis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2015-09-16 |
| Est. Completion | 2019-02-22 |
Why NCT02494635 stopped before completion
NCT02494635 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 4 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Laboratory Biomarker Analysis is the first listed.
NCT02494635 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02494635 about?
NCT02494635 is a clinical study titled "Ultrasound and Biomarker Tests in Predicting Cancer Aggressiveness in Tissue Samples of Patients With Bladder Cancer". This research trial studies two types of tests, an ultrasound test and a biomarker test, to see how well they predict how aggressive (invasive) bladder cancer is in samples from patients with bladder cancer. The aggressiveness of a tumor means how likely it is to invade the body and spread. The ultr...
What is the current status of trial NCT02494635?
This trial is currently terminated. The enrollment target is 4 participants. The study started on 2015-09-16. Estimated completion is 2019-02-22.
What interventions are being tested in trial NCT02494635?
The interventions under investigation include: Laboratory Biomarker Analysis (OTHER).
Who is sponsoring clinical trial NCT02494635?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
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