Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02494453 · ClinicalTrials.gov registry record
Pilot Study of Biomarkers and Cardiac MRI as Early Indicators of Cardiac Exposure Following Breast Radiotherapy
A clinical trial, sponsored by University of Michigan Rogel Cancer Center.
- Completed
- Registry status
- 23
- Enrollment target
NCT02494453 is a clinical trial that has completed, run by University of Michigan Rogel Cancer Center. The registered enrollment target is 23 participants.
The verdict
NCT02494453 has completed, sponsored by University of Michigan Rogel Cancer Center.
- COMPLETED
- Registry status
- 23 participants
- Enrollment target
Study Summary
Patients with breast cancer receive low doses to smaller volumes of the heart, but they also have an excellent long-term survival, so it is crucial to study the effects of low dose radiotherapy. Indeed, a recent study suggests that these effects can be seen within the first 5 years after treatment, and that there is no dose threshold. The investigators wish to develop imaging and blood biomarkers of cardiac exposure, as a first step to identifying patients at increased risk for cardiac effects. These patients can then be targeted for close monitoring and early intervention, potentially with statins or ACE inhibitors. Additionally, by characterizing a time-course and radiation dose-volume relationship, potentially real-time modifications can be made to radiotherapy (RT) field design for patients sensitive to RT effects. Finally, this information can be incorporated into better designs of treatment plans for future patients.
Interventions
- PROCEDURE Research Cardiac MRI
- PROCEDURE Biomarkers
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2015-06 |
| Est. Completion | 2017-07 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02494453
The ClinicalTrials.gov registry entry for NCT02494453 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan Rogel Cancer Center, which has 292 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Research Cardiac MRI is the first listed.
NCT02494453 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02494453 about?
NCT02494453 is a clinical study titled "Pilot Study of Biomarkers and Cardiac MRI as Early Indicators of Cardiac Exposure Following Breast Radiotherapy". Patients with breast cancer receive low doses to smaller volumes of the heart, but they also have an excellent long-term survival, so it is crucial to study the effects of low dose radiotherapy. Indeed, a recent study suggests that these effects can be seen within the first 5 years after treatment, ...
What is the current status of trial NCT02494453?
This trial is currently completed. The enrollment target is 23 participants. The study started on 2015-06. Estimated completion is 2017-07.
What interventions are being tested in trial NCT02494453?
The interventions under investigation include: Research Cardiac MRI (PROCEDURE), Biomarkers (PROCEDURE).
Who is sponsoring clinical trial NCT02494453?
This trial is sponsored by University of Michigan Rogel Cancer Center, which has 292 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.