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NCT02471846 · ClinicalTrials.gov registry record · Phase 1
A Study of GDC-0919 and Atezolizumab Combination Treatment in Participants With Locally Advanced or Metastatic Solid Tumors
A Phase 1 study, sponsored by Genentech.
- Completed
- Registry status
- Phase 1
- Development phase
- 158
- Enrollment target
NCT02471846: Completed Phase 1 study, sponsored by Genentech.
NCT02471846 is a Phase 1 study that has completed, run by Genentech. The registered enrollment target is 158 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (163% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02471846, a Phase 1 study, has completed, sponsored by Genentech.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 158 participants
- Enrollment target
Study Summary
This study will evaluate the safety, tolerability, and pharmacokinetics of the combination of GDC-0919 and atezolizumab in participants with locally advanced, recurrent, or metastatic incurable solid malignancy that has progressed after available standard therapy or for which standard therapy is ineffective, intolerable, or inappropriate. Participants will be enrolled in two stages, including a dose-escalation stage and an expansion stage.
Interventions
- DRUG Atezolizumab
- DRUG GDC-0919
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 158 participants |
| Start Date | 2015-07-28 |
| Est. Completion | 2019-10-02 |
| Phase | Phase 1 |
What the finished NCT02471846 record still lists
NCT02471846 is an interventional study that assigns participants to a tested intervention. The registered 158 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (163% higher).
The record links to 0 conditions, and to 2 interventions - of which Atezolizumab is the first listed.
NCT02471846 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02471846 about?
NCT02471846 is a clinical study titled "A Study of GDC-0919 and Atezolizumab Combination Treatment in Participants With Locally Advanced or Metastatic Solid Tumors". This study will evaluate the safety, tolerability, and pharmacokinetics of the combination of GDC-0919 and atezolizumab in participants with locally advanced, recurrent, or metastatic incurable solid malignancy that has progressed after available standard therapy or for which standard therapy is ine...
What is the current status of trial NCT02471846?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 158 participants. The study started on 2015-07-28. Estimated completion is 2019-10-02.
What interventions are being tested in trial NCT02471846?
The interventions under investigation include: Atezolizumab (DRUG), GDC-0919 (DRUG).
Who is sponsoring clinical trial NCT02471846?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02471846's enrollment target sits among peer trials
158 348th of 2000 higher than 1,650 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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