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COMPLETED NA

Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS

NCT02469675 · View on ClinicalTrials.gov ↗

Study Summary

Most neurological injuries such as spinal cord injuries (SCI) and amyotrophic lateral sclerosis (ALS) spare a portion of nerve circuitry. Strengthening spared nerve circuits may be an important method to improve functional recovery. In this study, the investigators aim to use non-invasive magnetic and electrical stimulation to strengthen motor circuits between the brain and hands. Magnetic stimulation will be used over the motor cortex (scalp). Two methods of electrical stimulation will be compared: stimulation of the median nerve at the wrist; or direct stimulation of the cervical spinal cord across the skin on the back of the neck. Several different combinations of magnetic and electrical stimulation will be compared to find the conditions that best strengthen nerve circuits between the brain and hands - "Fire Together, Wire Together". PLEASE NOTE, THIS IS A PRELIMINARY STUDY. This study is testing for temporary changes in nerve transmission and hand function. THERE IS NO EXPECTATION OF LONG-TERM BENEFIT FROM THIS STUDY. If we see temporary changes in this study, then future studies would focus on how to prolong that effect.

Interventions

  • DEVICE Transcranial magnetic stimulation
  • DEVICE Median nerve stimulation
  • DEVICE Cervical transcutaneous stimulation

Study Locations (1)

New York

  • James J. Peters VA Medical Center, Bronx, NY — The Bronx

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2015-06
Est. Completion 2018-07-31
Phase NA

Sponsor

Bronx VA Medical Center

7 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02469675

The ClinicalTrials.gov registry entry for NCT02469675 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 39 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bronx VA Medical Center, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Amyotrophic Lateral Sclerosis (ALS) appearing as the primary indexed condition, and to 3 interventions — of which Transcranial magnetic stimulation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02469675 reports 1 study location spanning 1 distinct geographic area — top geographies include New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02469675 about?

NCT02469675 is a clinical study titled "Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS". Most neurological injuries such as spinal cord injuries (SCI) and amyotrophic lateral sclerosis (ALS) spare a portion of nerve circuitry. Strengthening spared nerve circuits may be an important method to improve functional recovery. In this study, the investigators aim to use non-invasive magnetic ...

What is the current status of trial NCT02469675?

This trial is currently completed. It is a NA study. The enrollment target is 39 participants. The study started on 2015-06. Estimated completion is 2018-07-31.

What conditions does trial NCT02469675 study?

This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis (ALS), Spinal Cord Injury (SCI). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02469675?

The interventions under investigation include: Transcranial magnetic stimulation (DEVICE), Median nerve stimulation (DEVICE), Cervical transcutaneous stimulation (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02469675?

This trial is sponsored by Bronx VA Medical Center, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02469675 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial