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NCT02469675 · ClinicalTrials.gov registry record · NA
Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS
A NA study of Amyotrophic Lateral Sclerosis (ALS) and Spinal Cord Injury (SCI), sponsored by Bronx VA Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 39
- Enrollment target
- 1
- Study location
NCT02469675: Completed NA study of Amyotrophic Lateral Sclerosis (ALS) and Spinal Cord Injury (SCI), sponsored by Bronx VA Medical Center.
NCT02469675 is a NA study of Amyotrophic Lateral Sclerosis (ALS) and Spinal Cord Injury (SCI) that has completed, run by Bronx VA Medical Center. The registered enrollment target is 39 participants, below the 300-participant average among 18 other Amyotrophic Lateral Sclerosis (ALS) trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02469675, a NA study of Amyotrophic Lateral Sclerosis (ALS) and Spinal Cord Injury (SCI), has completed, sponsored by Bronx VA Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 39 participants
- Enrollment target
- 1
- Study location
Study Summary
Most neurological injuries such as spinal cord injuries (SCI) and amyotrophic lateral sclerosis (ALS) spare a portion of nerve circuitry. Strengthening spared nerve circuits may be an important method to improve functional recovery. In this study, the investigators aim to use non-invasive magnetic and electrical stimulation to strengthen motor circuits between the brain and hands. Magnetic stimulation will be used over the motor cortex (scalp). Two methods of electrical stimulation will be compared: stimulation of the median nerve at the wrist; or direct stimulation of the cervical spinal cord across the skin on the back of the neck. Several different combinations of magnetic and electrical stimulation will be compared to find the conditions that best strengthen nerve circuits between the brain and hands - "Fire Together, Wire Together". PLEASE NOTE, THIS IS A PRELIMINARY STUDY. This study is testing for temporary changes in nerve transmission and hand function. THERE IS NO EXPECTATION OF LONG-TERM BENEFIT FROM THIS STUDY. If we see temporary changes in this study, then future studies would focus on how to prolong that effect.
Conditions Studied
Interventions
- DEVICE Transcranial magnetic stimulation
- DEVICE Median nerve stimulation
- DEVICE Cervical transcutaneous stimulation
Study Locations (1)
New York
- James J. Peters VA Medical Center, Bronx, NY - The Bronx
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2015-06 |
| Est. Completion | 2018-07-31 |
| Phase | NA |
What the finished NCT02469675 record still lists
NCT02469675 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 300-participant average among 18 other Amyotrophic Lateral Sclerosis (ALS) trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Amyotrophic Lateral Sclerosis (ALS) appearing as the primary indexed condition, and to 3 interventions - of which Transcranial magnetic stimulation is the first listed.
NCT02469675 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02469675 about?
NCT02469675 is a clinical study titled "Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS". Most neurological injuries such as spinal cord injuries (SCI) and amyotrophic lateral sclerosis (ALS) spare a portion of nerve circuitry. Strengthening spared nerve circuits may be an important method to improve functional recovery. In this study, the investigators aim to use non-invasive magnetic ...
What is the current status of trial NCT02469675?
This trial is currently completed. It is a NA study. The enrollment target is 39 participants. The study started on 2015-06. Estimated completion is 2018-07-31.
What conditions does trial NCT02469675 study?
This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis (ALS), Spinal Cord Injury (SCI).
What interventions are being tested in trial NCT02469675?
The interventions under investigation include: Transcranial magnetic stimulation (DEVICE), Median nerve stimulation (DEVICE), Cervical transcutaneous stimulation (DEVICE).
Who is sponsoring clinical trial NCT02469675?
This trial is sponsored by Bronx VA Medical Center, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02469675 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amyotrophic Lateral Sclerosis (ALS)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02469675's enrollment target sits among peer trials
39 15th of 18 higher than 4 of 18 other Amyotrophic Lateral Sclerosis (ALS) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amyotrophic Lateral Sclerosis (ALS) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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