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ACTIVE NOT RECRUITING Phase 3

A Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma

NCT02455245 · View on ClinicalTrials.gov ↗

Study Summary

This study is trying to learn and understand if the chemotherapy drug called carboplatin works as well as the standard therapy. The standard therapy for Low Grade Glioma (LGG) in children and young adults is using a combination of carboplatin and vincristine. Studies in children have shown that the use of carboplatin alone has promise of being just as effective for treating LGG as standard therapy. Additionally, this study will try to understand if treatment with carboplatin alone is associated with an improved quality of life for LGG patients and their families.

Conditions Studied

Interventions

  • DRUG Carboplatin
  • DRUG Carboplatin and Vincristine

Study Locations (20)

Ohio

  • Children's Hospital Medical Center of Akron — Akron
  • Cincinnati Children's Hospital Medical Center — Cincinnati
  • Nationwide Children's Hospital — Columbus
  • Dayton Children's Hospital — Dayton

Missouri

  • Saint Louis University at SSM Cardinal Glennon Children's Medical Center — St Louis
  • Washington University School of Medicine — St Louis

Arizona

  • Phoenix Children's Hospital — Phoenix

California

  • Rady Children's Hospital — San Diego

Connecticut

  • Yale University — New Haven

Florida

  • Orlando Health, Inc. — Orlando

Illinois

  • Ann & Robert H. Lurie Children's Hosptial of Chicago — Chicago

Indiana

  • St. Vincent Peyton Manning Children's Hospital — Indianapolis

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2015-03
Est. Completion 2025-11-30
Phase Phase 3

Sponsor

Alicia Lenzen

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02455245

The ClinicalTrials.gov registry entry for NCT02455245 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 95 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alicia Lenzen, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Low Grade Glioma appearing as the primary indexed condition, and to 2 interventions — of which Carboplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02455245 reports 20 study locations spanning 16 distinct geographic areas — top geographies include Ohio, Missouri, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02455245 about?

NCT02455245 is a clinical study titled "A Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma". This study is trying to learn and understand if the chemotherapy drug called carboplatin works as well as the standard therapy. The standard therapy for Low Grade Glioma (LGG) in children and young adults is using a combination of carboplatin and vincristine. Studies in children have shown that the ...

What is the current status of trial NCT02455245?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 95 participants. The study started on 2015-03. Estimated completion is 2025-11-30.

What conditions does trial NCT02455245 study?

This clinical trial studies the following conditions: Low Grade Glioma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02455245?

The interventions under investigation include: Carboplatin (DRUG), Carboplatin and Vincristine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02455245?

This trial is sponsored by Alicia Lenzen, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02455245 being conducted?

This trial has 20 study locations across Arizona, California, Connecticut, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial