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NCT02441075 · ClinicalTrials.gov registry record · NA

70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014

A NA study, sponsored by Nationwide Children's Hospital.

Completed
Registry status
NA
Development phase
13
Enrollment target

NCT02441075: Completed NA study, sponsored by Nationwide Children's Hospital.

NCT02441075 is a NA study that has completed, run by Nationwide Children's Hospital. The registered enrollment target is 13 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02441075, a NA study, has completed, sponsored by Nationwide Children's Hospital.

COMPLETED
Registry status
NA
Development phase
13 participants
Enrollment target

Study Summary

This is for a study for patients that will be undergoing hematopoietic stem cell transplant (HSCT). For HSCT, patients will need a double lumen central venous line (CVL). One of the most common complications after an HSCT is Graft Versus Host Disease (GVHD).Tacrolimus or Cyclosporine along with methotrexate are used together in order to prevent GVHD. Normally these medications are given via the white lumen and blood is drawn via the unexposed red lumen to check the blood level of these medications. If these drugs are accidentally given via the wrong lumen (line) it could cause blood levels to be falsely high. This error could lead to the patient having to have peripheral blood draws that cause pain. The investigators are proposing adding an ethanol lock to your lumens (lines) to see if this would help clean the lines therefore preventing errors in blood tests and blood draws. An ethanol lock is a 70% alcohol which is injected into the CVL lumen and stays within the CVL as the CVL is capped.

Primary Outcome

Serum levels from both lumens will be compared after 2-hour ethanol lock placements. If the mean serum levels drawn at 8pm from both lumens are equivalent, the intervention will be considered effective.

Interventions

  • OTHER 70% Ethanol

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2014-05
Est. Completion 2016-01
Phase NA
Nationwide Children's Hospital

188 total trials

What the finished NCT02441075 record still lists

NCT02441075 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which 70% Ethanol is the first listed.

NCT02441075 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02441075 about?

NCT02441075 is a clinical study titled "70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014". This is for a study for patients that will be undergoing hematopoietic stem cell transplant (HSCT). For HSCT, patients will need a double lumen central venous line (CVL). One of the most common complications after an HSCT is Graft Versus Host Disease (GVHD).Tacrolimus or Cyclosporine along with meth...

What is the current status of trial NCT02441075?

This trial is currently completed. It is a NA study. The enrollment target is 13 participants. The study started on 2014-05. Estimated completion is 2016-01.

What interventions are being tested in trial NCT02441075?

The interventions under investigation include: 70% Ethanol (OTHER).

Who is sponsoring clinical trial NCT02441075?

This trial is sponsored by Nationwide Children's Hospital, which has 188 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02441075's enrollment target sits among peer trials

13 1911th of 2000 higher than 88 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02441075, the US trial registry maintained by the National Library of Medicine. NCT02441075 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.