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NCT02439138 · ClinicalTrials.gov registry record · Phase 2

Study of Phosphatidylinositol-3-kinase (PI3K) Inhibitor Idelalisib (GS-1101) in Waldenström Macroglobulinemia

A Phase 2 study, sponsored by Dana-Farber Cancer Institute.

Terminated
Registry status
Phase 2
Development phase
5
Enrollment target

NCT02439138: Clinical Trial Phase 2 study, sponsored by Dana-Farber Cancer Institute.

NCT02439138 is a Phase 2 study that was terminated before completion, run by Dana-Farber Cancer Institute. The registered enrollment target is 5 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02439138, a Phase 2 study, was terminated before completion, sponsored by Dana-Farber Cancer Institute.

TERMINATED
Registry status
Phase 2
Development phase
5 participants
Enrollment target

Study Summary

This research study is evaluating a drug called idelalisib (formerly known as GS-1101 or CAL-101) as a possible treatment for Waldenstrom's Macroglobulinemia (WM).

Primary Outcome

ORR measured by decrease in serum IgM level by at least 25% from baseline.

Interventions

  • DRUG GS-1101

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2015-10
Est. Completion 2016-04
Phase Phase 2
Dana-Farber Cancer Institute

781 total trials

Why NCT02439138 stopped before completion

NCT02439138 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which GS-1101 is the first listed.

NCT02439138 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02439138 about?

NCT02439138 is a clinical study titled "Study of Phosphatidylinositol-3-kinase (PI3K) Inhibitor Idelalisib (GS-1101) in Waldenström Macroglobulinemia". This research study is evaluating a drug called idelalisib (formerly known as GS-1101 or CAL-101) as a possible treatment for Waldenstrom's Macroglobulinemia (WM).

What is the current status of trial NCT02439138?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2015-10. Estimated completion is 2016-04.

What interventions are being tested in trial NCT02439138?

The interventions under investigation include: GS-1101 (DRUG).

Who is sponsoring clinical trial NCT02439138?

This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02439138's enrollment target sits among peer trials

5 2000th of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02439138, the US trial registry maintained by the National Library of Medicine. NCT02439138 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.