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NCT02438137 · ClinicalTrials.gov registry record · Phase 2
Dimethyl Fumarate for Obstructive Sleep Apnea
A Phase 2 study, sponsored by University of Michigan.
- Completed
- Registry status
- Phase 2
- Development phase
- 65
- Enrollment target
NCT02438137: Completed Phase 2 study, sponsored by University of Michigan.
NCT02438137 is a Phase 2 study that has completed, run by University of Michigan. The registered enrollment target is 65 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (51% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02438137, a Phase 2 study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 65 participants
- Enrollment target
Study Summary
The overall purpose of this study is to determine whether the oral medication dimethyl fumarate is an effective treatment for obstructive sleep apnea in patients who are unable, unwilling, or uneager to use positive airway pressure therapy.
Primary Outcome
For the 50 participants who had interpretable month 4 polysomnography (PSG) data available, mean change in sleep apnea severity, as measured by the mean change in respiratory disturbance index (RDI) between baseline (Month 0) PSG and Month 4 PSG, was calculated. The RDI represents the total number of apneas, hypopneas and respiratory-related arousals per hour of sleep.
Interventions
- DRUG Placebo
- DRUG Dimethyl fumarate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2015-05 |
| Est. Completion | 2016-05 |
| Phase | Phase 2 |
What the finished NCT02438137 record still lists
NCT02438137 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (51% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02438137 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02438137 about?
NCT02438137 is a clinical study titled "Dimethyl Fumarate for Obstructive Sleep Apnea". The overall purpose of this study is to determine whether the oral medication dimethyl fumarate is an effective treatment for obstructive sleep apnea in patients who are unable, unwilling, or uneager to use positive airway pressure therapy.
What is the current status of trial NCT02438137?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 65 participants. The study started on 2015-05. Estimated completion is 2016-05.
What interventions are being tested in trial NCT02438137?
The interventions under investigation include: Placebo (DRUG), Dimethyl fumarate (DRUG).
Who is sponsoring clinical trial NCT02438137?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02438137's enrollment target sits among peer trials
65 987th of 2000 higher than 1,005 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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