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NCT02432001 · ClinicalTrials.gov registry record
Radiologically Guided Biopsies of mCRPC
A clinical trial, sponsored by University of California, San Francisco.
- Completed
- Registry status
- 256
- Enrollment target
NCT02432001: Completed study, sponsored by University of California, San Francisco.
NCT02432001 is a clinical trial that has completed, run by University of California, San Francisco. The registered enrollment target is 256 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02432001 has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- 256 participants
- Enrollment target
Study Summary
The purpose of this study is to better understand how cancer treatment may affect cancer cells. The research will involve genetic, molecular, cellular, and immunologic experiments using blood and tumor specimens. It is hoped that the information gained from these studies will lead to a greater understanding of castrate-resistant prostate cancer and potentially, improvements in cancer treatment. This is a tissue collection protocol requiring image-guided biopsies of metastatic, castration-resistant prostate cancer (mCRPC). The investigators will focus on enrolling patients with metastatic CRPC who have progressed while receiving novel AR-targeted therapeutics such as abiraterone and enzalutamide. This population of patients was selected because resistance develops relatively rapidly following potent inhibitors of AR activity and the mechanisms of resistance have to be better understood. Without comprehensive analysis of mCRPC tumor, the investigators will never gain a full understanding of the biology driving resistance in human disease and developing rational co-targeting approaches will not be possible.
Primary Outcome
Determined by a gene-expression-based signature for Androgen Receptor activity having a probability of \>0.50
Interventions
- PROCEDURE Image-Guided Biopsies
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 256 participants |
| Start Date | 2013-02-22 |
| Est. Completion | 2020-01-01 |
What the finished NCT02432001 record still lists
NCT02432001 is an observational study that tracks outcomes without assigning an intervention. The registered 256 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Image-Guided Biopsies is the first listed.
NCT02432001 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02432001 about?
NCT02432001 is a clinical study titled "Radiologically Guided Biopsies of mCRPC". The purpose of this study is to better understand how cancer treatment may affect cancer cells. The research will involve genetic, molecular, cellular, and immunologic experiments using blood and tumor specimens. It is hoped that the information gained from these studies will lead to a greater under...
What is the current status of trial NCT02432001?
This trial is currently completed. The enrollment target is 256 participants. The study started on 2013-02-22. Estimated completion is 2020-01-01.
What interventions are being tested in trial NCT02432001?
The interventions under investigation include: Image-Guided Biopsies (PROCEDURE).
Who is sponsoring clinical trial NCT02432001?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
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