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NCT02431923 · ClinicalTrials.gov registry record

Ebola Virus Disease Survivors: Clinical and Immunologic Follow-up

A clinical trial, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
4,043
Enrollment target

NCT02431923: Completed study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT02431923 is a clinical trial that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 4,043 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02431923 has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
4,043 participants
Enrollment target

Study Summary

Background: \- Ebola is a lethal disease. A lot is still unknown about Ebola and its long-term effects. Researchers want to learn what ill health conditions Ebola survivors have. They want to learn if Ebola survivors can infect others in their household through close contact. They also want to learn if Ebola survivors are immune from getting Ebola again. To learn these things, they want to follow people in Liberia for 5 years. Objectives: \- To learn how Ebola affects the health of survivors and the people they live with. Eligibility: \- People in Liberia who had Ebola in the past 2 years, who share a household with someone who had Ebola, or who got ill and went to an Ebola Treatment Unit but were sent home because they did not have Ebola. Design: * Participants will be screened with family illness history, physical exam, and blood tests. They may have an eye exam. * Ebola survivors and those who went to a Treatment Unit but did not have Ebola will visit a clinic at 3, 6, and 12 months, then every 6 months for 5 years. At each visit, they will repeat the screening tests. * Participants who live with someone who had Ebola will have only the screening visit. But they may be asked to return for follow-up visits. These visits will help researchers learn more about the differences between those who have had Ebola and those who have not. * Participants brought to the NIH Clinical Center will have documentation of positive Ebola virus PCR and a clinical syndrome compatible with acute EVD. * The study will last 5 years.

Primary Outcome

longterm sequelae, ability to transmit Ebola, or long-term protective immunity in survivors convalescing from EVD

Trial Details

FieldValue
Enrollment Target 4,043 participants
Start Date 2017-12-02
Est. Completion 2021-04-30

What the finished NCT02431923 record still lists

NCT02431923 is an observational study that tracks outcomes without assigning an intervention. Its 4,043 participants enrollment target places it among the larger protocols in the corpus.

The record links to 0 conditions, and to 0 interventions.

NCT02431923 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02431923 about?

NCT02431923 is a clinical study titled "Ebola Virus Disease Survivors: Clinical and Immunologic Follow-up". Background: \- Ebola is a lethal disease. A lot is still unknown about Ebola and its long-term effects. Researchers want to learn what ill health conditions Ebola survivors have. They want to learn if Ebola survivors can infect others in their household through close contact. They also want to lear...

What is the current status of trial NCT02431923?

This trial is currently completed. The enrollment target is 4,043 participants. The study started on 2017-12-02. Estimated completion is 2021-04-30.

Who is sponsoring clinical trial NCT02431923?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT02431923, the US trial registry maintained by the National Library of Medicine. NCT02431923 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.