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NCT02430545 · ClinicalTrials.gov registry record · Phase 1
Understanding The Effect Of A Strong CYP3A4 Inducer On Glasdegib Pharmacokinetics
A Phase 1 study, sponsored by Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT02430545: Completed Phase 1 study, sponsored by Pfizer.
NCT02430545 is a Phase 1 study that has completed, run by Pfizer. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02430545, a Phase 1 study, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
The study also aims to determine the effect of a strong enzyme (CYP3A4) inducer-rifampin- on drug exposure of Glasdegib. This study will be conducted in healthy subjects given a single dose of glasdegib in each period.
Interventions
- DRUG Rifampin
- DRUG Glasdegib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2015-05 |
| Est. Completion | 2015-06 |
| Phase | Phase 1 |
What the finished NCT02430545 record still lists
NCT02430545 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Rifampin is the first listed.
NCT02430545 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02430545 about?
NCT02430545 is a clinical study titled "Understanding The Effect Of A Strong CYP3A4 Inducer On Glasdegib Pharmacokinetics". The study also aims to determine the effect of a strong enzyme (CYP3A4) inducer-rifampin- on drug exposure of Glasdegib. This study will be conducted in healthy subjects given a single dose of glasdegib in each period.
What is the current status of trial NCT02430545?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2015-05. Estimated completion is 2015-06.
What interventions are being tested in trial NCT02430545?
The interventions under investigation include: Rifampin (DRUG), Glasdegib (DRUG).
Who is sponsoring clinical trial NCT02430545?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02430545's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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