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NCT02425306 · ClinicalTrials.gov registry record · Phase 1

Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma

A Phase 1 study, sponsored by Craig L Slingluff, Jr.

Terminated
Registry status
Phase 1
Development phase
48
Enrollment target

NCT02425306 is a Phase 1 study that was terminated before completion, run by Craig L Slingluff, Jr. The registered enrollment target is 48 participants.

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The verdict

NCT02425306, a Phase 1 study, was terminated before completion, sponsored by Craig L Slingluff, Jr.

TERMINATED
Registry status
Phase 1
Development phase
48 participants
Enrollment target

Study Summary

This study evaluates whether it is safe to administer a peptide vaccine in combination with different adjuvants. Adjuvants are substances that may boost immune responses vaccines. In this study, the adjuvants are Montanide ISA-51, polyICLC and cyclophosphamide. This study will also evaluate the effects of the combination of the peptide vaccine and the adjuvants on the immune system. The investigators will monitor these effects by performing tests in the laboratory on participants' blood, a lymph node, and tissue from the sites of vaccination.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Montanide ISA-51
  • BIOLOGICAL 6MHP
  • DRUG polyICLC

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2015-05-12
Est. Completion 2018-01-08
Phase Phase 1

Sponsor

Craig L Slingluff, Jr

23 total trials

What the Registry Record Tells You About NCT02425306

The ClinicalTrials.gov registry entry for NCT02425306 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Craig L Slingluff, Jr, which has 23 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Cyclophosphamide is the first listed.

NCT02425306 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02425306 about?

NCT02425306 is a clinical study titled "Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma". This study evaluates whether it is safe to administer a peptide vaccine in combination with different adjuvants. Adjuvants are substances that may boost immune responses vaccines. In this study, the adjuvants are Montanide ISA-51, polyICLC and cyclophosphamide. This study will also evaluate the effe...

What is the current status of trial NCT02425306?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2015-05-12. Estimated completion is 2018-01-08.

What interventions are being tested in trial NCT02425306?

The interventions under investigation include: Cyclophosphamide (DRUG), Montanide ISA-51 (DRUG), 6MHP (BIOLOGICAL), polyICLC (DRUG).

Who is sponsoring clinical trial NCT02425306?

This trial is sponsored by Craig L Slingluff, Jr, which has 23 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.