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NCT02422940 · ClinicalTrials.gov registry record · Phase 3

Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine.

A Phase 3 study, sponsored by Acorda Therapeutics.

Terminated
Registry status
Phase 3
Development phase
294
Enrollment target

NCT02422940: Clinical Trial Phase 3 study, sponsored by Acorda Therapeutics.

NCT02422940 is a Phase 3 study that was terminated before completion, run by Acorda Therapeutics. The registered enrollment target is 294 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02422940, a Phase 3 study, was terminated before completion, sponsored by Acorda Therapeutics.

TERMINATED
Registry status
Phase 3
Development phase
294 participants
Enrollment target

Study Summary

This is an extension study to evaluate the long-term safety, tolerability, and efficacy of two dose strengths of dalfampridine-ER.

Primary Outcome

This extension study was designed to evaluate long-term safety, tolerability, and efficacy of dalfampridine-ER (extended release) in adult subjects with chronic post-ischemic stroke walking deficits. Subjects who had completed the placebo-controlled DALF-PS-1016 core study were eligible to enroll regardless of whether they had received active drug or placebo in the core study.

Interventions

  • DRUG dalfampridine-ER 7.5 mg
  • DRUG dalfampridine-ER 10 mg

Trial Details

FieldValue
Enrollment Target 294 participants
Start Date 2015-04
Est. Completion 2017-01
Phase Phase 3
Acorda Therapeutics

36 total trials

Why NCT02422940 stopped before completion

NCT02422940 is an interventional study that assigns participants to a tested intervention. The registered 294 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 2 interventions - of which dalfampridine-ER 7.5 mg is the first listed.

NCT02422940 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02422940 about?

NCT02422940 is a clinical study titled "Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine.". This is an extension study to evaluate the long-term safety, tolerability, and efficacy of two dose strengths of dalfampridine-ER.

What is the current status of trial NCT02422940?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 294 participants. The study started on 2015-04. Estimated completion is 2017-01.

What interventions are being tested in trial NCT02422940?

The interventions under investigation include: dalfampridine-ER 7.5 mg (DRUG), dalfampridine-ER 10 mg (DRUG).

Who is sponsoring clinical trial NCT02422940?

This trial is sponsored by Acorda Therapeutics, which has 36 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02422940's enrollment target sits among peer trials

294 1166th of 2000 higher than 835 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02422940, the US trial registry maintained by the National Library of Medicine. NCT02422940 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.