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NCT02421497 · ClinicalTrials.gov registry record
MRI Technical Development and Applications in Kidney Disease
A clinical trial, sponsored by University of Minnesota.
- Not yet
- Registry status
- 180
- Enrollment target
NCT02421497: Clinical Trial study, sponsored by University of Minnesota.
NCT02421497 is a clinical trial that has not yet begun recruiting, run by University of Minnesota. The registered enrollment target is 180 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02421497 has not yet begun recruiting, sponsored by University of Minnesota.
- NOT YET RECRUITING
- Registry status
- 180 participants
- Enrollment target
Study Summary
Magnetic resonance imaging (MRI), as a non-invasive and non-contrast enhanced technique, has the potential to improve patient health care and management. The overall objective of proposed project is to: 1. develop, customize, and optimize anatomic and functional MRI methods, 2. explore the use of MRI methods to study CKD and evaluate post-transplant kidneys, and 3. investigate the potential of MRI in the diagnosis, prognosis, and monitoring of the progression of renal dysfunction. In addition to direct studies of the kidney, brain MRI studies will also be performed to identify the cerebrovascular and cognitive effects of chronic renal function deficiency and medical treatment (e.g. hemodialysis and immunosuppression). The brain and kidneys have similar vascular bed, and both are susceptible to vascular injury, which provides the pathological basis for the widely recognized association of reduced renal function with prevalent cerebrovascular diseases (CVDs) and cognitive impairment (CI). The MRI methods in the brain will be applied to explore the origins for widely observed CVDs and prevalent cognitive impairment (CI) in kidney disease patients.
Primary Outcome
MRI measures will be evaluated both globally and regionally (e.g. frontal lobe and the hippocampus of the brain, renal cortex and medulla in each and both kidneys). The correlations among MRI measurements, the degree of CKD disease (as evaluated by eGFR) and the severity of cognitive impairment will be assessed using both cross-sectional and longitudinal analyses. Non-parametric analysis approach will be used instead of parametric if appropriate.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2028-06-30 |
| Est. Completion | 2029-12-30 |
What is known before NCT02421497 opens enrollment
NCT02421497 is an observational study that tracks outcomes without assigning an intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT02421497 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02421497 about?
NCT02421497 is a clinical study titled "MRI Technical Development and Applications in Kidney Disease". Magnetic resonance imaging (MRI), as a non-invasive and non-contrast enhanced technique, has the potential to improve patient health care and management. The overall objective of proposed project is to: 1. develop, customize, and optimize anatomic and functional MRI methods, 2. explore the use of M...
What is the current status of trial NCT02421497?
This trial is currently not yet recruiting. The enrollment target is 180 participants. The study started on 2028-06-30. Estimated completion is 2029-12-30.
Who is sponsoring clinical trial NCT02421497?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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