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NCT02400112 · ClinicalTrials.gov registry record · Phase 4
Local Application of Vancomycin Powder in Grade I-IIIA Open Fractures
A Phase 4 study, sponsored by University of Tennessee.
- Terminated
- Registry status
- Phase 4
- Development phase
- 11
- Enrollment target
NCT02400112: Clinical Trial Phase 4 study, sponsored by University of Tennessee.
NCT02400112 is a Phase 4 study that was terminated before completion, run by University of Tennessee. The registered enrollment target is 11 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02400112, a Phase 4 study, was terminated before completion, sponsored by University of Tennessee.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 11 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if local administration of vancomycin powder at the site of Grade I-IIIA open fractures at the time of surgery will be an efficacious method to lower infection rates in open fracture treatment and to elucidate any detrimental effects of applying vancomycin powder at the site of open fractures.
Primary Outcome
Infections will be considered clinically significant if they require a return to the operating suite for surgical debridement. These infections will be classified as acute infections and/or chronic osteomyelitis. Superficial skin infections will be treated with local wound care, oral antibiotics and incision and drainage (as indicated). Deep infections and chronic osteomyelitis will be treated with staged serial surgical debridement, hardware removal (as indicated), culture specific IV antibioti
Interventions
- DRUG Vancomycin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2015-03 |
| Est. Completion | 2018-10 |
| Phase | Phase 4 |
Why NCT02400112 stopped before completion
NCT02400112 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Vancomycin is the first listed.
NCT02400112 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02400112 about?
NCT02400112 is a clinical study titled "Local Application of Vancomycin Powder in Grade I-IIIA Open Fractures". The purpose of this study is to determine if local administration of vancomycin powder at the site of Grade I-IIIA open fractures at the time of surgery will be an efficacious method to lower infection rates in open fracture treatment and to elucidate any detrimental effects of applying vancomycin p...
What is the current status of trial NCT02400112?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 11 participants. The study started on 2015-03. Estimated completion is 2018-10.
What interventions are being tested in trial NCT02400112?
The interventions under investigation include: Vancomycin (DRUG).
Who is sponsoring clinical trial NCT02400112?
This trial is sponsored by University of Tennessee, which has 96 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02400112's enrollment target sits among peer trials
11 1931st of 2000 higher than 61 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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