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NCT02393625 · ClinicalTrials.gov registry record · Phase 1

Study of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lung Cancer

A Phase 1 study of ALK-positive NSCLC, sponsored by Novartis Pharmaceuticals.

Active
Registry status
Phase 1
Development phase
57
Enrollment target
12
Study locations

NCT02393625 is a Phase 1 study of ALK-positive NSCLC that is active but no longer recruiting, run by Novartis Pharmaceuticals. The registered enrollment target is 57 participants. The trial reports 12 study locations across 9 states.

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The verdict

NCT02393625, a Phase 1 study of ALK-positive NSCLC, is active but no longer recruiting, sponsored by Novartis Pharmaceuticals.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
57 participants
Enrollment target
12
Study locations

Study Summary

This is an open label multi center trial to determine the safety and efficacy of ceritinib in combination with nivolumab in ALK-positive NSCLC patients

Conditions Studied

Interventions

  • DRUG Nivolumab
  • DRUG Ceritinib (LDK378)

Study Locations (12)

Other

  • Novartis Investigative Site - Hong Kong
  • Novartis Investigative Site - Singapore
  • Novartis Investigative Site - Barcelona

Massachusetts

  • Massachusetts General Hospital - Boston
  • Massachusetts General Hospital Thoracic Oncolgoy - Boston

Arizona

  • Mayo Clinic - Arizona - Scottsdale

Pennsylvania

  • Fox Chase Cancer Center - Philadelphia

Victoria

  • Novartis Investigative Site - Heidelberg

Vlaams Brabant

  • Novartis Investigative Site - Leuven

Ontario

  • Novartis Investigative Site - Toronto

MI

  • Novartis Investigative Site - Milan

Trial Details

FieldValue
Enrollment Target 57 participants
Start Date 2015-05-27
Est. Completion 2027-04-09
Phase Phase 1

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT02393625

The ClinicalTrials.gov registry entry for NCT02393625 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 57 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with ALK-positive NSCLC appearing as the primary indexed condition, and to 2 interventions - of which Nivolumab is the first listed.

NCT02393625 reports 12 study locations spanning 9 distinct geographic areas - top geographies include Other, Massachusetts, Arizona.

Frequently Asked Questions

What is clinical trial NCT02393625 about?

NCT02393625 is a clinical study titled "Study of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lung Cancer". This is an open label multi center trial to determine the safety and efficacy of ceritinib in combination with nivolumab in ALK-positive NSCLC patients

What is the current status of trial NCT02393625?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 57 participants. The study started on 2015-05-27. Estimated completion is 2027-04-09.

What conditions does trial NCT02393625 study?

This clinical trial studies the following conditions: ALK-positive NSCLC.

What interventions are being tested in trial NCT02393625?

The interventions under investigation include: Nivolumab (DRUG), Ceritinib (LDK378) (DRUG).

Who is sponsoring clinical trial NCT02393625?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02393625 being conducted?

This trial has 12 study locations across Arizona, Massachusetts, Pennsylvania, Victoria, Vlaams Brabant. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.