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NCT02354833 · ClinicalTrials.gov registry record · Phase 4

Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery

A Phase 4 study, sponsored by West Virginia University.

Completed
Registry status
Phase 4
Development phase
85
Enrollment target

NCT02354833: Completed Phase 4 study, sponsored by West Virginia University.

NCT02354833 is a Phase 4 study that has completed, run by West Virginia University. The registered enrollment target is 85 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (84% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02354833, a Phase 4 study, has completed, sponsored by West Virginia University.

COMPLETED
Registry status
Phase 4
Development phase
85 participants
Enrollment target

Study Summary

The purpose of the study is to determine if a medication called phenylephrine, which helps to control blood pressure, is more effective as a continuous intravenous (IV) infusion compared to continuous IV norepinephrine in maintaining blood pressure during a spinal anesthetic for a cesarean delivery. Good blood pressure control has been shown to decrease nausea and vomiting during and after cesarean delivery under spinal anesthesia. For elective cesarean delivery, all participants will receive spinal anesthesia with a local anesthetic and morphine (provides long term pain control after cesarean delivery). This study plans to enroll 80 pregnant research subjects 18 years and above. Patients will be randomly assigned according to a computer generated system to be in one of two groups.

Primary Outcome

Number of rescue boluses to maintain the SBP within 100-120% of baseline

Interventions

  • DRUG Norepinephrine
  • DRUG Phenylephrine

Trial Details

FieldValue
Enrollment Target 85 participants
Start Date 2014-08
Est. Completion 2015-08
Phase Phase 4
West Virginia University

122 total trials

What the finished NCT02354833 record still lists

NCT02354833 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 85 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (84% lower).

The record links to 0 conditions, and to 2 interventions - of which Norepinephrine is the first listed.

NCT02354833 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02354833 about?

NCT02354833 is a clinical study titled "Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery". The purpose of the study is to determine if a medication called phenylephrine, which helps to control blood pressure, is more effective as a continuous intravenous (IV) infusion compared to continuous IV norepinephrine in maintaining blood pressure during a spinal anesthetic for a cesarean delivery....

What is the current status of trial NCT02354833?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 85 participants. The study started on 2014-08. Estimated completion is 2015-08.

What interventions are being tested in trial NCT02354833?

The interventions under investigation include: Norepinephrine (DRUG), Phenylephrine (DRUG).

Who is sponsoring clinical trial NCT02354833?

This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02354833's enrollment target sits among peer trials

85 928th of 2000 higher than 1,072 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02354833, the US trial registry maintained by the National Library of Medicine. NCT02354833 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.