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NCT02322320 · ClinicalTrials.gov registry record · Phase 3

Continued, Long-Term Follow-Up and Lenalidomide Maintenance Therapy for Patients on BMT CTN 0702 Protocol (BMT CTN 07LT)

A Phase 3 study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

Completed
Registry status
Phase 3
Development phase
273
Enrollment target

NCT02322320: Completed Phase 3 study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

NCT02322320 is a Phase 3 study that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 273 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02322320, a Phase 3 study, has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

COMPLETED
Registry status
Phase 3
Development phase
273 participants
Enrollment target

Study Summary

This study is designed to compare long-term outcomes among patients randomized on the BMT CTN 0702 protocol (NCT01109004), "A Trial of Single Autologous Transplant with or without Consolidation Therapy versus Tandem Autologous Transplant with Lenalidomide Maintenance for Patients with Multiple Myeloma". It is hypothesized that use of novel anti-myeloma agents will improve long-term progression-free survival (PFS) after high-dose melphalan followed by autologous hematopoietic cell transplantation (HCT) as compared to a second autologous transplantation.

Primary Outcome

This analysis includes all randomized subjects from the BMT CTN 0702 protocol classified according to their randomized treatment assignment (intention-to-treat). Progression-free survival is defined as survival without disease progression or initiation of non-protocol anti-myeloma therapy. To account for loss to follow-up, the Kaplan-Meier estimator was used to estimate progression-free survival during the 5 year post-randomization follow-up period.

Interventions

  • DRUG Lenalidomide

Trial Details

FieldValue
Enrollment Target 273 participants
Start Date 2015-03
Est. Completion 2019-06-07
Phase Phase 3

What the finished NCT02322320 record still lists

NCT02322320 is an interventional study that assigns participants to a tested intervention. The registered 273 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (65% lower).

The record links to 0 conditions, and to 1 intervention - of which Lenalidomide is the first listed.

NCT02322320 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02322320 about?

NCT02322320 is a clinical study titled "Continued, Long-Term Follow-Up and Lenalidomide Maintenance Therapy for Patients on BMT CTN 0702 Protocol (BMT CTN 07LT)". This study is designed to compare long-term outcomes among patients randomized on the BMT CTN 0702 protocol (NCT01109004), "A Trial of Single Autologous Transplant with or without Consolidation Therapy versus Tandem Autologous Transplant with Lenalidomide Maintenance for Patients with Multiple Myelo...

What is the current status of trial NCT02322320?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 273 participants. The study started on 2015-03. Estimated completion is 2019-06-07.

What interventions are being tested in trial NCT02322320?

The interventions under investigation include: Lenalidomide (DRUG).

Who is sponsoring clinical trial NCT02322320?

This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02322320's enrollment target sits among peer trials

273 1213th of 2000 higher than 787 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02322320, the US trial registry maintained by the National Library of Medicine. NCT02322320 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.