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NCT02308371 · ClinicalTrials.gov registry record · NA
PPV to Guide Fluid Management in the PICU
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 100
- Enrollment target
NCT02308371: Completed NA study, sponsored by University of North Carolina, Chapel Hill.
NCT02308371 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02308371, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
Study Summary
Children who are critically ill often require large amounts of fluid during their acute illness. It has been shown in multiple studies that appropriate administration of fluid decreases morbidity and mortality, but giving too much fluid can also cause increased morbidity and mortality. It is often difficult to discern from physical exam, vital signs and labs if the amount of fluid that has been given is appropriate or if a pediatric patient requires more fluid. Pulse pressure variation (PPV) is the change in blood pressure when a patient is on a ventilator or breathing machine. PPV has been used in multiple adult studies to help predict fluid needs in a critically ill patient. In this study, we would like to investigate if PPV can help better predict if critically ill pediatric patients in the pediatric intensive care unit (PICU) need fluid. The investigators hope that by having the additional information that PPV can provide, physicians can more judiciously give fluid and thereby improve morbidity of critically ill patients in the PICU.
Primary Outcome
Total fluid (ml/kg/day) given during the first 48 hours of enrollment
Interventions
- DEVICE Automated Pulse Pressure Variation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2014-11 |
| Est. Completion | 2016-06 |
| Phase | NA |
What the finished NCT02308371 record still lists
NCT02308371 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which Automated Pulse Pressure Variation is the first listed.
NCT02308371 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02308371 about?
NCT02308371 is a clinical study titled "PPV to Guide Fluid Management in the PICU". Children who are critically ill often require large amounts of fluid during their acute illness. It has been shown in multiple studies that appropriate administration of fluid decreases morbidity and mortality, but giving too much fluid can also cause increased morbidity and mortality. It is often d...
What is the current status of trial NCT02308371?
This trial is currently completed. It is a NA study. The enrollment target is 100 participants. The study started on 2014-11. Estimated completion is 2016-06.
What interventions are being tested in trial NCT02308371?
The interventions under investigation include: Automated Pulse Pressure Variation (DEVICE).
Who is sponsoring clinical trial NCT02308371?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02308371's enrollment target sits among peer trials
100 840th of 2000 higher than 1,081 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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