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NCT02306993 · ClinicalTrials.gov registry record

Sickle Cell Hemoglobinopathies and Bone Health

A clinical trial of Sickle Cell Disease and Sickle Cell Trait, sponsored by UConn Health.

Active
Registry status
45
Enrollment target
1
Study location

NCT02306993 is a study of Sickle Cell Disease and Sickle Cell Trait that is active but no longer recruiting, run by UConn Health. The registered enrollment target is 45 participants, below the 293-participant average among 213 other Sickle Cell Disease trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02306993, a study of Sickle Cell Disease and Sickle Cell Trait, is active but no longer recruiting, sponsored by UConn Health.

ACTIVE NOT RECRUITING
Registry status
45 participants
Enrollment target
1
Study location

Study Summary

This research study has two purposes. The first purpose is to determine whether having sickle cell trait (SCT) is a risk factor for the development of bone thinning at an earlier age than expected. Nearly 10% of African Americans (AA) carry sickle cell trait and most of them are unaware of it. African Americans are less likely to develop thin bones than whites, but if they sustain a bone fracture, they are more likely to die from it. We believe having sickle cell trait may lead to bone thinning and predispose a subset of African Americans to dangerously thin bones. The second purpose is to try to understand why individuals with sickle cell disease (SCD) have thinner bones than healthy individuals do. Doctors have already discovered that people with sickle cell disease have very thin bones, but they have not determined why. Our study will try to identify whether the bone thinning is from the body not making enough bone or from the body losing bone once it is made.

Conditions Studied

Sickle Cell Disease Sickle Cell Trait

Interventions

  • OTHER Healthy volunteers without SCT
  • OTHER Healthy volunteers with SCT
  • OTHER Volunteers with SCD

Study Locations (1)

Connecticut

  • UConn Health - Farmington

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2014-05
Est. Completion 2025-12

Sponsor

UConn Health

178 total trials

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What the Registry Record Tells You About NCT02306993

The ClinicalTrials.gov registry entry for NCT02306993 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 293-participant average among 213 other Sickle Cell Disease trials with a reported enrollment target (85% lower). The listed sponsor is UConn Health, which has 178 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Sickle Cell Disease appearing as the primary indexed condition, and to 3 interventions - of which Healthy volunteers without SCT is the first listed.

NCT02306993 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT02306993 about?

NCT02306993 is a clinical study titled "Sickle Cell Hemoglobinopathies and Bone Health". This research study has two purposes. The first purpose is to determine whether having sickle cell trait (SCT) is a risk factor for the development of bone thinning at an earlier age than expected. Nearly 10% of African Americans (AA) carry sickle cell trait and most of them are unaware of it. Afric...

What is the current status of trial NCT02306993?

This trial is currently active not recruiting. The enrollment target is 45 participants. The study started on 2014-05. Estimated completion is 2025-12.

What conditions does trial NCT02306993 study?

This clinical trial studies the following conditions: Sickle Cell Disease, Sickle Cell Trait.

What interventions are being tested in trial NCT02306993?

The interventions under investigation include: Healthy volunteers without SCT (OTHER), Healthy volunteers with SCT (OTHER), Volunteers with SCD (OTHER).

Who is sponsoring clinical trial NCT02306993?

This trial is sponsored by UConn Health, which has 178 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02306993 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.