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An Observational Study in Differentiated Thyroid Cancer Which is Radioactive Iodine (RAI) Refractory to Assess the Use of Multikinase Inhibitors
NCT02303444 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of the study was to assess the use of Multikinase Inhibitors (MKIs) in the treatment of patients with a progressive differentiated thyroid carcinoma (DTC) refractory to radioactive iodine (RAI) who do not have any symptoms.
Conditions Studied
Interventions
- DRUG Sorafenib (Nexavar, BAY43-9006)
- DRUG Other Multikinase inhibitors
Study Locations (20)
Other
- — Multiple Locations
- — Multiple Locations
- — Multiple Locations
- — Multiple Locations
California
- — Los Angeles
- — Torrance
Alabama
- — Birmingham
Colorado
- — Aurora
District of Columbia
- — Washington D.C.
Florida
- — Plantation
Georgia
- — Atlanta
Hawaii
- — Honolulu
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 667 participants |
| Start Date | 2015-04-08 |
| Est. Completion | 2020-07-24 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02303444
The ClinicalTrials.gov registry entry for NCT02303444 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 667 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bayer, which has 143 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Thyroid Neoplasms appearing as the primary indexed condition, and to 2 interventions — of which Sorafenib (Nexavar, BAY43-9006) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02303444 reports 20 study locations spanning 16 distinct geographic areas — top geographies include Other, California, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02303444 about?
NCT02303444 is a clinical study titled "An Observational Study in Differentiated Thyroid Cancer Which is Radioactive Iodine (RAI) Refractory to Assess the Use of Multikinase Inhibitors". The purpose of the study was to assess the use of Multikinase Inhibitors (MKIs) in the treatment of patients with a progressive differentiated thyroid carcinoma (DTC) refractory to radioactive iodine (RAI) who do not have any symptoms.
What is the current status of trial NCT02303444?
This trial is currently completed. The enrollment target is 667 participants. The study started on 2015-04-08. Estimated completion is 2020-07-24.
What conditions does trial NCT02303444 study?
This clinical trial studies the following conditions: Thyroid Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02303444?
The interventions under investigation include: Sorafenib (Nexavar, BAY43-9006) (DRUG), Other Multikinase inhibitors (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02303444?
This trial is sponsored by Bayer, which has 143 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02303444 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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