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NCT02302157 · ClinicalTrials.gov registry record · Phase 1
Dose Escalation Study of AST-OPC1 in Spinal Cord Injury
A Phase 1 study, sponsored by Lineage Cell Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
NCT02302157: Completed Phase 1 study, sponsored by Lineage Cell Therapeutics.
NCT02302157 is a Phase 1 study that has completed, run by Lineage Cell Therapeutics. The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02302157, a Phase 1 study, has completed, sponsored by Lineage Cell Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety of cross sequential escalating doses of AST-OPC1 administered among 5 cohorts at a single time-point between 21 and 42 days post injury, inclusively, to subjects with subacute cervical spinal cord injuries (SCI).
Primary Outcome
Numbers of adverse events within 1 year (365 days) that are related to AST-OPC1 injection
Interventions
- BIOLOGICAL AST-OPC1
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2015-03 |
| Est. Completion | 2018-12 |
| Phase | Phase 1 |
What the finished NCT02302157 record still lists
NCT02302157 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).
The record links to 0 conditions, and to 1 intervention - of which AST-OPC1 is the first listed.
NCT02302157 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02302157 about?
NCT02302157 is a clinical study titled "Dose Escalation Study of AST-OPC1 in Spinal Cord Injury". The purpose of this study is to evaluate the safety of cross sequential escalating doses of AST-OPC1 administered among 5 cohorts at a single time-point between 21 and 42 days post injury, inclusively, to subjects with subacute cervical spinal cord injuries (SCI).
What is the current status of trial NCT02302157?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2015-03. Estimated completion is 2018-12.
What interventions are being tested in trial NCT02302157?
The interventions under investigation include: AST-OPC1 (BIOLOGICAL).
Who is sponsoring clinical trial NCT02302157?
This trial is sponsored by Lineage Cell Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02302157's enrollment target sits among peer trials
25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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