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NCT02299336 · ClinicalTrials.gov registry record · Phase 4

Long-Term Efficacy & Safety of Aflibercept IVT for the Treatment of DME in Subjects Who Completed the VISTA-DME Trial

A Phase 4 study, sponsored by Greater Houston Retina Research.

Completed
Registry status
Phase 4
Development phase
60
Enrollment target

NCT02299336 is a Phase 4 study that has completed, run by Greater Houston Retina Research. The registered enrollment target is 60 participants.

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The verdict

NCT02299336, a Phase 4 study, has completed, sponsored by Greater Houston Retina Research.

COMPLETED
Registry status
Phase 4
Development phase
60 participants
Enrollment target

Study Summary

The Endurance Trial is a phase IV open label clinical study to assess the need for ongoing intravitreal aflibercept injections after the 3-year VISTA DME (VGFT-OD-1009; NCT01363440) end-point. Subjects will be treated with intravitreal aflibercept injections pro re nata (PRN) based on the presence of CR-DME (Clinically Relevant-DME). In addition, subjects who meet re-treatment criteria will be eligible for focal laser treatment every 90 days.

Interventions

  • DRUG Aflibercept
  • PROCEDURE Focal Laser

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2014-11-24
Est. Completion 2017-01-09
Phase Phase 4

Sponsor

Greater Houston Retina Research

8 total trials

What the Registry Record Tells You About NCT02299336

The ClinicalTrials.gov registry entry for NCT02299336 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Greater Houston Retina Research, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Aflibercept is the first listed.

NCT02299336 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02299336 about?

NCT02299336 is a clinical study titled "Long-Term Efficacy & Safety of Aflibercept IVT for the Treatment of DME in Subjects Who Completed the VISTA-DME Trial". The Endurance Trial is a phase IV open label clinical study to assess the need for ongoing intravitreal aflibercept injections after the 3-year VISTA DME (VGFT-OD-1009; NCT01363440) end-point. Subjects will be treated with intravitreal aflibercept injections pro re nata (PRN) based on the presence o...

What is the current status of trial NCT02299336?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2014-11-24. Estimated completion is 2017-01-09.

What interventions are being tested in trial NCT02299336?

The interventions under investigation include: Aflibercept (DRUG), Focal Laser (PROCEDURE).

Who is sponsoring clinical trial NCT02299336?

This trial is sponsored by Greater Houston Retina Research, which has 8 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.