Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02294032 · ClinicalTrials.gov registry record
The Role of B Cells in Kidney Allograft Dysfunction
A clinical trial of Transplantation Infection and Kidney; Complications, Allograft, sponsored by Loma Linda University.
- Completed
- Registry status
- 180
- Enrollment target
- 1
- Study location
NCT02294032: Completed study of Transplantation Infection and Kidney; Complications, Allograft, sponsored by Loma Linda University.
NCT02294032 is a study of Transplantation Infection and Kidney; Complications, Allograft that has completed, run by Loma Linda University. The registered enrollment target is 180 participants, below the 251-participant average among 4 other Transplantation Infection trials with a reported enrollment target (28% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02294032, a study of Transplantation Infection and Kidney; Complications, Allograft, has completed, sponsored by Loma Linda University.
- COMPLETED
- Registry status
- 180 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to understand the role of specific B cells in activating or repressing an anti-allograft immune response after kidney transplantation. In this study, blood will be collected from kidney transplant patients during different timepoints, prior to and after their transplant. Knowledge gained from study findings will be used to develop therapeutic strategies to prevent antibody-mediated rejection, which is a major cause of long-term graft loss in kidney transplant patients.
Primary Outcome
Blood will be collected from kidney transplant patients prior to and after their transplant (1-, 3-, 6-, 12-, 18-, 24-, 36-, 48-, and 60- months post-transplant). We will try to better understand the role of specific B-cells after kidney transplant by using enzyme-linked immunosorbent assay (ELISA).
Conditions Studied
Interventions
- DRUG Immunosuppressive Agents
Study Locations (1)
California
- Loma Linda University Medical Center, Transplantation Institute - Loma Linda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2014-08-28 |
| Est. Completion | 2023-04-24 |
What the finished NCT02294032 record still lists
NCT02294032 is an observational study that tracks outcomes without assigning an intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 251-participant average among 4 other Transplantation Infection trials with a reported enrollment target (28% lower).
The record links to 2 conditions, with Transplantation Infection appearing as the primary indexed condition, and to 1 intervention - of which Immunosuppressive Agents is the first listed.
NCT02294032 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT02294032 about?
NCT02294032 is a clinical study titled "The Role of B Cells in Kidney Allograft Dysfunction". The purpose of this study is to understand the role of specific B cells in activating or repressing an anti-allograft immune response after kidney transplantation. In this study, blood will be collected from kidney transplant patients during different timepoints, prior to and after their transplant....
What is the current status of trial NCT02294032?
This trial is currently completed. The enrollment target is 180 participants. The study started on 2014-08-28. Estimated completion is 2023-04-24.
What conditions does trial NCT02294032 study?
This clinical trial studies the following conditions: Transplantation Infection, Kidney; Complications, Allograft.
What interventions are being tested in trial NCT02294032?
The interventions under investigation include: Immunosuppressive Agents (DRUG).
Who is sponsoring clinical trial NCT02294032?
This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02294032 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Transplantation Infection
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients
RECRUITING · Phase 2
-
High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients
RECRUITING · Phase 2
-
High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients
ACTIVE NOT RECRUITING · Phase 2
-
Cidofovir Versus Best Supportive Care for Hemorrhagic Cystitis
ACTIVE NOT RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01558804 · 180 participants
GRoup A StrePtococcus
- NCT02932176 · 180 participants
Machine Learning for Handheld Vascular Studies
- NCT03384563 · 180 participants · Phase 4
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
- NCT03423628 · 180 participants · Phase 1
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI