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COMPLETED

The Role of B Cells in Kidney Allograft Dysfunction

NCT02294032 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to understand the role of specific B cells in activating or repressing an anti-allograft immune response after kidney transplantation. In this study, blood will be collected from kidney transplant patients during different timepoints, prior to and after their transplant. Knowledge gained from study findings will be used to develop therapeutic strategies to prevent antibody-mediated rejection, which is a major cause of long-term graft loss in kidney transplant patients.

Interventions

  • DRUG Immunosuppressive Agents

Study Locations (1)

California

  • Loma Linda University Medical Center, Transplantation Institute — Loma Linda

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2014-08-28
Est. Completion 2023-04-24

Sponsor

Loma Linda University

191 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02294032

The ClinicalTrials.gov registry entry for NCT02294032 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Loma Linda University, which has 191 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Transplantation Infection appearing as the primary indexed condition, and to 1 intervention — of which Immunosuppressive Agents is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02294032 reports 1 study location spanning 1 distinct geographic area — top geographies include California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02294032 about?

NCT02294032 is a clinical study titled "The Role of B Cells in Kidney Allograft Dysfunction". The purpose of this study is to understand the role of specific B cells in activating or repressing an anti-allograft immune response after kidney transplantation. In this study, blood will be collected from kidney transplant patients during different timepoints, prior to and after their transplant....

What is the current status of trial NCT02294032?

This trial is currently completed. The enrollment target is 180 participants. The study started on 2014-08-28. Estimated completion is 2023-04-24.

What conditions does trial NCT02294032 study?

This clinical trial studies the following conditions: Transplantation Infection, Kidney; Complications, Allograft. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02294032?

The interventions under investigation include: Immunosuppressive Agents (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02294032?

This trial is sponsored by Loma Linda University, which has 191 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02294032 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial