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NCT02289833 · ClinicalTrials.gov registry record · Phase 2

A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor (HER)2 Immunohistochemistry (IHC)-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

A Phase 2 study, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 2
Development phase
49
Enrollment target

NCT02289833 is a Phase 2 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 49 participants.

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The verdict

NCT02289833, a Phase 2 study, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 2
Development phase
49 participants
Enrollment target

Study Summary

This is a Phase 2, multicenter study designed to evaluate the efficacy and safety of trastuzumab emtansine administered as a single-agent in participants with HER2-positive (HER2 IHC 2+ or HER2 IHC 3+) advanced or metastatic NSCLC. Participants will be treated with trastuzumab emtansine administered intravenously at a dose of 3.6 milligrams per kilogram (mg/kg) on Day 1 of 21-day cycles until disease progression (as assessed by the investigator), unmanageable toxicity, or study termination by the Sponsor, whichever occurs first.

Interventions

  • DRUG Trastuzumab Emtansine

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2014-12-15
Est. Completion 2018-08-20
Phase Phase 2

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT02289833

The ClinicalTrials.gov registry entry for NCT02289833 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Trastuzumab Emtansine is the first listed.

NCT02289833 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02289833 about?

NCT02289833 is a clinical study titled "A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor (HER)2 Immunohistochemistry (IHC)-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)". This is a Phase 2, multicenter study designed to evaluate the efficacy and safety of trastuzumab emtansine administered as a single-agent in participants with HER2-positive (HER2 IHC 2+ or HER2 IHC 3+) advanced or metastatic NSCLC. Participants will be treated with trastuzumab emtansine administered...

What is the current status of trial NCT02289833?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 49 participants. The study started on 2014-12-15. Estimated completion is 2018-08-20.

What interventions are being tested in trial NCT02289833?

The interventions under investigation include: Trastuzumab Emtansine (DRUG).

Who is sponsoring clinical trial NCT02289833?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.