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NCT02274870 · ClinicalTrials.gov registry record · Phase 4
Liposomal Bupivacaine for Post Operative Pain After Knee Replacement Surgery
A Phase 4 study, sponsored by Northwell Health.
- Completed
- Registry status
- Phase 4
- Development phase
- 65
- Enrollment target
NCT02274870: Completed Phase 4 study, sponsored by Northwell Health.
NCT02274870 is a Phase 4 study that has completed, run by Northwell Health. The registered enrollment target is 65 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02274870, a Phase 4 study, has completed, sponsored by Northwell Health.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 65 participants
- Enrollment target
Study Summary
Continuous femoral nerve blocks (CFNB) provide effective pain control to patients undergoing total knee replacement (TKR). However the resulting motor blockade can lead to decreased quadriceps muscle strength and delayed functional recovery.The purpose of this study is to compare the effect of Liposome Bupivacaine infiltration into the knee to CFNB on pain control and functional recovery
Primary Outcome
Pain intensity at maximum knee flexion measured using a 0-10 visual analog scale. Higher values represent a higher pain intensity or worse outcome.
Interventions
- DRUG Bupivacaine HCl
- DRUG Liposome Bupivacaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2014-11 |
| Est. Completion | 2017-01 |
| Phase | Phase 4 |
What the finished NCT02274870 record still lists
NCT02274870 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which Bupivacaine HCl is the first listed.
NCT02274870 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02274870 about?
NCT02274870 is a clinical study titled "Liposomal Bupivacaine for Post Operative Pain After Knee Replacement Surgery". Continuous femoral nerve blocks (CFNB) provide effective pain control to patients undergoing total knee replacement (TKR). However the resulting motor blockade can lead to decreased quadriceps muscle strength and delayed functional recovery.The purpose of this study is to compare the effect of Lipos...
What is the current status of trial NCT02274870?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 65 participants. The study started on 2014-11. Estimated completion is 2017-01.
What interventions are being tested in trial NCT02274870?
The interventions under investigation include: Bupivacaine HCl (DRUG), Liposome Bupivacaine (DRUG).
Who is sponsoring clinical trial NCT02274870?
This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02274870's enrollment target sits among peer trials
65 1091st of 2000 higher than 903 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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