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COMPLETED Phase 2

Pembrolizumab in Treating Patients With Advanced Merkel Cell Cancer

NCT02267603 · View on ClinicalTrials.gov ↗

Study Summary

This phase II trial studies how well pembrolizumab works in treating patients with Merkel cell cancer that cannot be removed by surgery or controlled with treatment, or has spread to other parts of the body. Pembrolizumab may stimulate the immune system to identify and destroy cancer cells.

Interventions

  • BIOLOGICAL Pembrolizumab
  • OTHER Laboratory Biomarker Analysis

Study Locations (13)

California

  • Stanford Cancer Institute Palo Alto — Palo Alto
  • UCSF Medical Center-Mount Zion — San Francisco

Louisiana

  • Louisiana State University Health Science Center — New Orleans
  • University Medical Center New Orleans — New Orleans

Connecticut

  • Yale University — New Haven

Florida

  • Moffitt Cancer Center — Tampa

Georgia

  • Emory University Hospital/Winship Cancer Institute — Atlanta

Maryland

  • Johns Hopkins University/Sidney Kimmel Cancer Center — Baltimore

New York

  • Mount Sinai Hospital — New York

North Carolina

  • Duke University Medical Center — Durham

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2014-11-25
Est. Completion 2021-12-15
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

2,390 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02267603

The ClinicalTrials.gov registry entry for NCT02267603 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 2,390 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Recurrent Merkel Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions — of which Pembrolizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02267603 reports 13 study locations spanning 11 distinct geographic areas — top geographies include California, Louisiana, Connecticut. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02267603 about?

NCT02267603 is a clinical study titled "Pembrolizumab in Treating Patients With Advanced Merkel Cell Cancer". This phase II trial studies how well pembrolizumab works in treating patients with Merkel cell cancer that cannot be removed by surgery or controlled with treatment, or has spread to other parts of the body. Pembrolizumab may stimulate the immune system to identify and destroy cancer cells.

What is the current status of trial NCT02267603?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2014-11-25. Estimated completion is 2021-12-15.

What conditions does trial NCT02267603 study?

This clinical trial studies the following conditions: Recurrent Merkel Cell Carcinoma, Stage III Merkel Cell Carcinoma AJCC v7, Stage IIIA Merkel Cell Carcinoma AJCC v7, Stage IIIB Merkel Cell Carcinoma AJCC v7, Stage IV Merkel Cell Carcinoma AJCC v7. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02267603?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Laboratory Biomarker Analysis (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02267603?

This trial is sponsored by National Cancer Institute (NCI), which has 2,390 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02267603 being conducted?

This trial has 13 study locations across California, Connecticut, Florida, Georgia, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial