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NCT02257619 · ClinicalTrials.gov registry record · Phase 2
Study of Itacitinib in Combination With Docetaxel in Subjects With Non-Small Cell Lung Cancer
A Phase 2 study, sponsored by Incyte Corporation.
- Terminated
- Registry status
- Phase 2
- Development phase
- 9
- Enrollment target
NCT02257619: Clinical Trial Phase 2 study, sponsored by Incyte Corporation.
NCT02257619 is a Phase 2 study that was terminated before completion, run by Incyte Corporation. The registered enrollment target is 9 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02257619, a Phase 2 study, was terminated before completion, sponsored by Incyte Corporation.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 9 participants
- Enrollment target
Study Summary
The primary objectives of this study were to evaluate the safety and tolerability of itacitinib in combination with docetaxel and to select doses for further evaluation (Part 1, safety run-in portion), and to evaluate and compare the overall survival of subjects with previously treated advanced or metastatic non-small cell lung cancer (NSCLC) when treated with itacitinib in combination with docetaxel versus docetaxel alone (Part 2, randomized portion).
Primary Outcome
Number of participants with DLT for the determination of the Maximum Tolerated Dose (MTD).
Interventions
- DRUG Itacitinib
- DRUG docetaxel
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2014-09-24 |
| Est. Completion | 2016-04-05 |
| Phase | Phase 2 |
Why NCT02257619 stopped before completion
NCT02257619 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which Itacitinib is the first listed.
NCT02257619 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02257619 about?
NCT02257619 is a clinical study titled "Study of Itacitinib in Combination With Docetaxel in Subjects With Non-Small Cell Lung Cancer". The primary objectives of this study were to evaluate the safety and tolerability of itacitinib in combination with docetaxel and to select doses for further evaluation (Part 1, safety run-in portion), and to evaluate and compare the overall survival of subjects with previously treated advanced or m...
What is the current status of trial NCT02257619?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 9 participants. The study started on 2014-09-24. Estimated completion is 2016-04-05.
What interventions are being tested in trial NCT02257619?
The interventions under investigation include: Itacitinib (DRUG), docetaxel (DRUG).
Who is sponsoring clinical trial NCT02257619?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02257619's enrollment target sits among peer trials
9 1989th of 2000 higher than 11 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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