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NCT02253992 · ClinicalTrials.gov registry record · Phase 1

An Investigational Immuno-therapy Study to Determine the Safety of Urelumab Given in Combination With Nivolumab in Solid Tumors and B-cell Non-Hodgkin's Lymphoma

A Phase 1 study, sponsored by Bristol-Myers Squibb.

Terminated
Registry status
Phase 1
Development phase
232
Enrollment target

NCT02253992: Clinical Trial Phase 1 study, sponsored by Bristol-Myers Squibb.

NCT02253992 is a Phase 1 study that was terminated before completion, run by Bristol-Myers Squibb. The registered enrollment target is 232 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (287% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02253992, a Phase 1 study, was terminated before completion, sponsored by Bristol-Myers Squibb.

TERMINATED
Registry status
Phase 1
Development phase
232 participants
Enrollment target

Study Summary

The purpose of this study is to determine which doses of Urelumab and Nivolumab are safe and tolerable when they are given together.

Interventions

  • BIOLOGICAL Nivolumab
  • BIOLOGICAL Urelumab

Trial Details

FieldValue
Enrollment Target 232 participants
Start Date 2014-09-29
Est. Completion 2019-05-24
Phase Phase 1
Bristol-Myers Squibb

1,025 total trials

Why NCT02253992 stopped before completion

NCT02253992 is an interventional study that assigns participants to a tested intervention. The registered 232 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (287% higher).

The record links to 0 conditions, and to 2 interventions - of which Nivolumab is the first listed.

NCT02253992 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02253992 about?

NCT02253992 is a clinical study titled "An Investigational Immuno-therapy Study to Determine the Safety of Urelumab Given in Combination With Nivolumab in Solid Tumors and B-cell Non-Hodgkin's Lymphoma". The purpose of this study is to determine which doses of Urelumab and Nivolumab are safe and tolerable when they are given together.

What is the current status of trial NCT02253992?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 232 participants. The study started on 2014-09-29. Estimated completion is 2019-05-24.

What interventions are being tested in trial NCT02253992?

The interventions under investigation include: Nivolumab (BIOLOGICAL), Urelumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT02253992?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02253992's enrollment target sits among peer trials

232 216th of 2000 higher than 1,784 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02253992, the US trial registry maintained by the National Library of Medicine. NCT02253992 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.