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NCT02247479 · ClinicalTrials.gov registry record · Phase 3
A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
A Phase 3 study, sponsored by Hoffmann-La Roche.
- Terminated
- Registry status
- Phase 3
- Development phase
- 906
- Enrollment target
NCT02247479: Clinical Trial Phase 3 study, sponsored by Hoffmann-La Roche.
NCT02247479 is a Phase 3 study that was terminated before completion, run by Hoffmann-La Roche. The registered enrollment target is 906 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02247479, a Phase 3 study, was terminated before completion, sponsored by Hoffmann-La Roche.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 906 participants
- Enrollment target
Study Summary
This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).
Primary Outcome
The change in GA lesion area was measured by FAF and analysis of FAF images was performed by the central reading center. A positive change from baseline indicates an increase in size of GA lesion area (worsening; disease progression).
Interventions
- OTHER Sham
- DRUG Lampalizumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 906 participants |
| Start Date | 2014-09-18 |
| Est. Completion | 2018-01-29 |
| Phase | Phase 3 |
Why NCT02247479 stopped before completion
NCT02247479 is an interventional study that assigns participants to a tested intervention. The registered 906 participants enrollment target is mid-sized for trials with a published cap, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (17% higher).
The record links to 0 conditions, and to 2 interventions - of which Sham is the first listed.
NCT02247479 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02247479 about?
NCT02247479 is a clinical study titled "A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration". This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).
What is the current status of trial NCT02247479?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 906 participants. The study started on 2014-09-18. Estimated completion is 2018-01-29.
What interventions are being tested in trial NCT02247479?
The interventions under investigation include: Sham (OTHER), Lampalizumab (DRUG).
Who is sponsoring clinical trial NCT02247479?
This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02247479's enrollment target sits among peer trials
906 347th of 2000 higher than 1,654 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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