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NCT02247037 · ClinicalTrials.gov registry record
Patient-derived Xenograft (PDX) Modeling of Treatment Response for Triple Negative Breast Cancer
A clinical trial of Triple Negative Breast Cancer, sponsored by Icahn School of Medicine at Mount Sinai.
- Completed
- Registry status
- 68
- Enrollment target
- 1
- Study location
NCT02247037: Completed study of Triple Negative Breast Cancer, sponsored by Icahn School of Medicine at Mount Sinai.
NCT02247037 is a study of Triple Negative Breast Cancer that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 68 participants, below the 246-participant average among 118 other Triple Negative Breast Cancer trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02247037, a study of Triple Negative Breast Cancer, has completed, sponsored by Icahn School of Medicine at Mount Sinai.
- COMPLETED
- Registry status
- 68 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will determine if patient-derived tumor xenograft (PDX) mouse models can serve as a reliable model for treatment response for individual patients with triple negative breast cancer. The collection of patient tumor tissue will also provide insight into the mechanisms of therapeutic resistance for those individuals. Ultimately, this study will enhance our understanding of the genomic basis for treatment response for triple negative cancer on an individual basis, while having the potential to suggest new therapeutic options for high-risk triple negative breast cancer patients with residual disease post neoadjuvant.
Primary Outcome
Tumor response in patients will be categorized as: Progressive Disease, Static Response, Partial Response, Complete Response
Conditions Studied
Interventions
- OTHER Chemotherapy
Study Locations (1)
New York
- Dubin Breast Center of The Tisch Cancer Institute at Mount Sinai - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2014-07 |
| Est. Completion | 2019-01-22 |
What the finished NCT02247037 record still lists
NCT02247037 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 246-participant average among 118 other Triple Negative Breast Cancer trials with a reported enrollment target (72% lower).
The record links to 1 condition, with Triple Negative Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Chemotherapy is the first listed.
NCT02247037 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02247037 about?
NCT02247037 is a clinical study titled "Patient-derived Xenograft (PDX) Modeling of Treatment Response for Triple Negative Breast Cancer". This study will determine if patient-derived tumor xenograft (PDX) mouse models can serve as a reliable model for treatment response for individual patients with triple negative breast cancer. The collection of patient tumor tissue will also provide insight into the mechanisms of therapeutic resista...
What is the current status of trial NCT02247037?
This trial is currently completed. The enrollment target is 68 participants. The study started on 2014-07. Estimated completion is 2019-01-22.
What conditions does trial NCT02247037 study?
This clinical trial studies the following conditions: Triple Negative Breast Cancer.
What interventions are being tested in trial NCT02247037?
The interventions under investigation include: Chemotherapy (OTHER).
Who is sponsoring clinical trial NCT02247037?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02247037 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Triple Negative Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02247037's enrollment target sits among peer trials
68 63rd of 118 higher than 56 of 118 other Triple Negative Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Triple Negative Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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