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NCT02242578 · ClinicalTrials.gov registry record · NA
Treating Refractory Schizophrenia With rTMS
A NA study, sponsored by Seton Healthcare Family.
- Terminated
- Registry status
- NA
- Development phase
- 2
- Enrollment target
NCT02242578: Clinical Trial NA study, sponsored by Seton Healthcare Family.
NCT02242578 is a NA study that was terminated before completion, run by Seton Healthcare Family. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02242578, a NA study, was terminated before completion, sponsored by Seton Healthcare Family.
- TERMINATED
- Registry status
- NA
- Development phase
- 2 participants
- Enrollment target
Study Summary
Symptomatic treatment of the negative symptoms in schizophrenia (such as social withdrawal, affective flattening, poor motivation, and apathy) with medications and psychotherapy are almost non-existent, whereas treatment of the positive symptoms (hallucinations and delusions) has been more effective with psychotropic medications. The proposed research on human subjects using a non-invasive technology (such as repetitive transcranial magnetic stimulation \[rTMS\]) will provide efficacy data for treating negative symptoms. The hypotheses are that 1) Cerebellar stimulation will cause activation of thalamic and frontal cortical networks associated with attentional processes as a component of the "distracted" affect of schizophrenia; 2) Cerebellar stimulation will cause activation of the reticular activating system (RAS), and this will allow the "mutism", which is a negative symptom, to be partially improved.
Primary Outcome
Participants will receive baseline and post-treatment protocol neuropsychiatric measures. These rating scales are accepted and standardized.
Interventions
- DEVICE 1 Hz rTMS
- DEVICE 10 Hz rTMS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2011-01-24 |
| Est. Completion | 2018-06-11 |
| Phase | NA |
Why NCT02242578 stopped before completion
NCT02242578 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which 1 Hz rTMS is the first listed.
NCT02242578 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02242578 about?
NCT02242578 is a clinical study titled "Treating Refractory Schizophrenia With rTMS". Symptomatic treatment of the negative symptoms in schizophrenia (such as social withdrawal, affective flattening, poor motivation, and apathy) with medications and psychotherapy are almost non-existent, whereas treatment of the positive symptoms (hallucinations and delusions) has been more effective...
What is the current status of trial NCT02242578?
This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2011-01-24. Estimated completion is 2018-06-11.
What interventions are being tested in trial NCT02242578?
The interventions under investigation include: 1 Hz rTMS (DEVICE), 10 Hz rTMS (DEVICE).
Who is sponsoring clinical trial NCT02242578?
This trial is sponsored by Seton Healthcare Family, which has 15 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02242578's enrollment target sits among peer trials
2 1997th of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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