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NCT02233816 · ClinicalTrials.gov registry record · Phase 2

Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal Virus-Like-Particle Quadrivalent Influenza Vaccine in Adults

A Phase 2 study, sponsored by Medicago.

Completed
Registry status
Phase 2
Development phase
300
Enrollment target

NCT02233816 is a Phase 2 study that has completed, run by Medicago. The registered enrollment target is 300 participants.

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The verdict

NCT02233816, a Phase 2 study, has completed, sponsored by Medicago.

COMPLETED
Registry status
Phase 2
Development phase
300 participants
Enrollment target

Study Summary

A phase II trial multicenter, observer-blind, randomized, dose-ranging, placebo-controlled study to evaluate the immunogenicity, safety, and tolerability of a single intramuscular injection of plant-derived Seasonal VLP Quadrivalent Influenza Vaccine administered to healthy adults 18-49 years of age. A total of three hundred subjects will be randomized in four (4) groups of 75 subjects to receive one injection of either a low, a medium, or a high dose level of the quadrivalent VLP influenza vaccine or the placebo preparation (100 millimolar (mM) phosphate buffer + 150 mM sodium chloride (NaCl) + 0.01% Tween 80).

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Low dose of quadrivalent VLP vaccine
  • BIOLOGICAL Medium dose of quadrivalent VLP vaccine
  • BIOLOGICAL High dose of quadrivalent VLP vaccine

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2014-07-28
Est. Completion 2015-06-22
Phase Phase 2

Sponsor

Medicago

9 total trials

What the Registry Record Tells You About NCT02233816

The ClinicalTrials.gov registry entry for NCT02233816 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medicago, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT02233816 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02233816 about?

NCT02233816 is a clinical study titled "Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal Virus-Like-Particle Quadrivalent Influenza Vaccine in Adults". A phase II trial multicenter, observer-blind, randomized, dose-ranging, placebo-controlled study to evaluate the immunogenicity, safety, and tolerability of a single intramuscular injection of plant-derived Seasonal VLP Quadrivalent Influenza Vaccine administered to healthy adults 18-49 years of age...

What is the current status of trial NCT02233816?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 300 participants. The study started on 2014-07-28. Estimated completion is 2015-06-22.

What interventions are being tested in trial NCT02233816?

The interventions under investigation include: Placebo (BIOLOGICAL), Low dose of quadrivalent VLP vaccine (BIOLOGICAL), Medium dose of quadrivalent VLP vaccine (BIOLOGICAL), High dose of quadrivalent VLP vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT02233816?

This trial is sponsored by Medicago, which has 9 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.