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NCT02233647 · ClinicalTrials.gov registry record · Early Phase 1
Phendimetrazine and Cocaine
A Early Phase 1 study, sponsored by William Stoops.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 11
- Enrollment target
NCT02233647: Completed Early Phase 1 study, sponsored by William Stoops.
NCT02233647 is a Early Phase 1 study that has completed, run by William Stoops. The registered enrollment target is 11 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (79% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02233647, a Early Phase 1 study, has completed, sponsored by William Stoops.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 11 participants
- Enrollment target
Study Summary
This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will be conducted in which the subjective and physiological effects of cocaine are evaluated during maintenance on placebo and phendimetrazine.
Primary Outcome
Systolic blood pressure was measured with an automated monitor. Higher values represent greater systolic pressure. Peak scores were calculated from multiple assessments for each cocaine dose under both phendimetrazine and placebo maintenance conditions.
Interventions
- DRUG Placebo
- DRUG Cocaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2014-09 |
| Est. Completion | 2015-12 |
| Phase | Early Phase 1 |
What the finished NCT02233647 record still lists
NCT02233647 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (79% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02233647 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02233647 about?
NCT02233647 is a clinical study titled "Phendimetrazine and Cocaine". This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will be conducted in which the subjective and physiological effects of cocaine are evaluated during maintenance on placebo a...
What is the current status of trial NCT02233647?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 11 participants. The study started on 2014-09. Estimated completion is 2015-12.
What interventions are being tested in trial NCT02233647?
The interventions under investigation include: Placebo (DRUG), Cocaine (DRUG).
Who is sponsoring clinical trial NCT02233647?
This trial is sponsored by William Stoops, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02233647's enrollment target sits among peer trials
11 1600th of 2000 higher than 373 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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