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NCT02223338 · ClinicalTrials.gov registry record · NA
Bacterial Resistance in Patients Receiving Post-Intravitreal Injection Antibiotics
A NA study, sponsored by Loma Linda University.
- Completed
- Registry status
- NA
- Development phase
- 120
- Enrollment target
NCT02223338 is a NA study that has completed, run by Loma Linda University. The registered enrollment target is 120 participants.
The verdict
NCT02223338, a NA study, has completed, sponsored by Loma Linda University.
- COMPLETED
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
Study Summary
1. Background: Over 1 million intravitreal injections are performed annually in the United States. The most devastating complication related to these injections is endophthalmitis, with an incidence of 0.02 - 0.1% per injection. Techniques aimed at prevention of this complication have been studied, though emergence rates of antibiotic resistant bacteria in a single clinic population comparing antiseptic technique with iodine vs. use of post-injection second generation fluoroquinolones has not been reported in the literature. 2. Objectives: The purpose of the study is to help determine the best way to prevent infection and limit antibiotic resistance in patients receiving eye injections. 3. Procedures Involved (Research Interventions): After the patient is chosen based on inclusion criteria and agrees to participate in the study, exclusion criteria will be reviewed, cognizance will be determined, informed consent and HIPAA compliance forms will be signed. At this point and prior to the instillation of ophthalmic medications, a Rayon swab will be passed along the inferior fornix of the study eye while the patient looks up and the examiner lowers the lower eyelid. The swab will then be used to inoculate chocolate agar and a blood agar culture plates and a glass slide. These will be brought to the FMO microbiology department for culture and Gram stain. All Staphylococcus aureus and coagulase negative Staphylococcus species identified will be subjected to sensitivity testing using the Gram Positive antibiotic panel available at Loma Linda, with the addition of ciprofloxacin.
Interventions
- DRUG Ciprofloxacin
- DRUG Standard Aseptic Technique
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2014-10 |
| Est. Completion | 2016-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02223338
The ClinicalTrials.gov registry entry for NCT02223338 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Loma Linda University, which has 237 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Ciprofloxacin is the first listed.
NCT02223338 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02223338 about?
NCT02223338 is a clinical study titled "Bacterial Resistance in Patients Receiving Post-Intravitreal Injection Antibiotics". 1. Background: Over 1 million intravitreal injections are performed annually in the United States. The most devastating complication related to these injections is endophthalmitis, with an incidence of 0.02 - 0.1% per injection. Techniques aimed at prevention of this complication have been studied, ...
What is the current status of trial NCT02223338?
This trial is currently completed. It is a NA study. The enrollment target is 120 participants. The study started on 2014-10. Estimated completion is 2016-05.
What interventions are being tested in trial NCT02223338?
The interventions under investigation include: Ciprofloxacin (DRUG), Standard Aseptic Technique (DRUG).
Who is sponsoring clinical trial NCT02223338?
This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.
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