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NCT02222610 · ClinicalTrials.gov registry record · Phase 2

Study of the Efficacy and Tolerability of Intravitreal Injections of Ranibizumab Compared to Intravitreal Injections of Ranibizumab Combined With Targeted Retinal Photocoagulation to Treat Radiation Retinopathy.

A Phase 2 study, sponsored by Greater Houston Retina Research.

Completed
Registry status
Phase 2
Development phase
40
Enrollment target

NCT02222610: Completed Phase 2 study, sponsored by Greater Houston Retina Research.

NCT02222610 is a Phase 2 study that has completed, run by Greater Houston Retina Research. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02222610, a Phase 2 study, has completed, sponsored by Greater Houston Retina Research.

COMPLETED
Registry status
Phase 2
Development phase
40 participants
Enrollment target

Study Summary

The purpose of this study is to assess the tolerability and efficacy of ranibizumab treatment administered in subjects with radiation retinopathy

Primary Outcome

Early Treatment Diabetic Retinopathy Study (ETDRS) Best-Corrected Visual Acuity (BCVA) utilizes the ETDRS visual acuity chart to measure vision in clinical trials. Standard unit of measure is the number of letters subjects are able to read on the chart.

Interventions

  • DRUG 0.5 mg ranibizumab
  • PROCEDURE Targeted Retinal Photocoagulation (TRP)

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2014-09-23
Est. Completion 2019-03
Phase Phase 2
Greater Houston Retina Research

8 total trials

What the finished NCT02222610 record still lists

NCT02222610 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 2 interventions - of which 0.5 mg ranibizumab is the first listed.

NCT02222610 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02222610 about?

NCT02222610 is a clinical study titled "Study of the Efficacy and Tolerability of Intravitreal Injections of Ranibizumab Compared to Intravitreal Injections of Ranibizumab Combined With Targeted Retinal Photocoagulation to Treat Radiation Retinopathy.". The purpose of this study is to assess the tolerability and efficacy of ranibizumab treatment administered in subjects with radiation retinopathy

What is the current status of trial NCT02222610?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2014-09-23. Estimated completion is 2019-03.

What interventions are being tested in trial NCT02222610?

The interventions under investigation include: 0.5 mg ranibizumab (DRUG), Targeted Retinal Photocoagulation (TRP) (PROCEDURE).

Who is sponsoring clinical trial NCT02222610?

This trial is sponsored by Greater Houston Retina Research, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02222610's enrollment target sits among peer trials

40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02222610, the US trial registry maintained by the National Library of Medicine. NCT02222610 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.