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NCT02220023 · ClinicalTrials.gov registry record · Early Phase 1

Dynamic Assessment of Right Ventricular Function With Inhaled Nitric Oxide During Cardiac MRI

A Early Phase 1 study, sponsored by Vanderbilt University.

Completed
Registry status
Early Phase 1
Development phase
17
Enrollment target

NCT02220023: Completed Early Phase 1 study, sponsored by Vanderbilt University.

NCT02220023 is a Early Phase 1 study that has completed, run by Vanderbilt University. The registered enrollment target is 17 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02220023, a Early Phase 1 study, has completed, sponsored by Vanderbilt University.

COMPLETED
Registry status
Early Phase 1
Development phase
17 participants
Enrollment target

Study Summary

The purpose of the study is to measure RV ejection fraction (RVEF), pulmonary flow, and pulmonary perfusion before and after exposure to inhaled nitric oxide in patients with pulmonary arterial hypertension (PAH) who are known to be vasodilator-responsive based on invasive catheterization as well as healthy subjects. Measurements will also be made after high flow oxygen alone to test the relative vasodilatory effect of oxygen and NO. The investigators hypothesize is that inhaled nitric oxide during cardiac MRI can be used to measure dynamic changes in RV-pulmonary vascular function in patients with vasodilator-responsive PAH.

Interventions

  • DRUG INOmax Inhalation

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2014-07
Est. Completion 2017-02
Phase Early Phase 1
Vanderbilt University

430 total trials

What the finished NCT02220023 record still lists

NCT02220023 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (68% lower).

The record links to 0 conditions, and to 1 intervention - of which INOmax Inhalation is the first listed.

NCT02220023 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02220023 about?

NCT02220023 is a clinical study titled "Dynamic Assessment of Right Ventricular Function With Inhaled Nitric Oxide During Cardiac MRI". The purpose of the study is to measure RV ejection fraction (RVEF), pulmonary flow, and pulmonary perfusion before and after exposure to inhaled nitric oxide in patients with pulmonary arterial hypertension (PAH) who are known to be vasodilator-responsive based on invasive catheterization as well as...

What is the current status of trial NCT02220023?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 17 participants. The study started on 2014-07. Estimated completion is 2017-02.

What interventions are being tested in trial NCT02220023?

The interventions under investigation include: INOmax Inhalation (DRUG).

Who is sponsoring clinical trial NCT02220023?

This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02220023's enrollment target sits among peer trials

17 1350th of 2000 higher than 632 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02220023, the US trial registry maintained by the National Library of Medicine. NCT02220023 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.