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NCT02209493 · ClinicalTrials.gov registry record · NA
Effects of Nopales (Opuntia Spp.) on Lipoprotein Profile and Oxidative Stress in Moderately Hypercholesterolemic Adults
A NA study, sponsored by Arizona State University.
- Completed
- Registry status
- NA
- Development phase
- 27
- Enrollment target
NCT02209493: Completed NA study, sponsored by Arizona State University.
NCT02209493 is a NA study that has completed, run by Arizona State University. The registered enrollment target is 27 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02209493, a NA study, has completed, sponsored by Arizona State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 27 participants
- Enrollment target
Study Summary
In light of the high CVD morbidity and mortality, promoting simple interventions to improve serum lipids and decrease oxidative stress are warranted to help prevent chronic diseases. Because of their fiber content, nopales (prickly pear cactus pads from the Opuntia species) are commonly regarded among Mexicans as a medicinal plant for glycemic and cholesterol control. However, the literature documenting their purported hypocholesterolemic potential is scarce. Given the unique composition and potential benefits of nopales, their use may be an ideal approach as an adjunct therapy for the reduction in cardiometabolic risk factors. Therefore, the aim of this study is to evaluate the efficacy of a 2-week intervention with nopales pads for the reduction of established CVD risk factors (serum lipids) in comparison to a control food with lower antioxidant and fiber content (cucumber) among adults with moderate hypercholesterolemia in a randomized controlled crossover trial. Because limited data exists on the effects of nopales supplementation on other factors associated with cardiometabolic risk, an exploratory assessment of how biomarkers of insulin sensitivity, inflammation (high sensitivity C-reactive protein \[hsCRP\]) and oxidative stress (LDL oxidizability and total antioxidant capacity) will also be conducted.
Primary Outcome
Total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides.
Interventions
- BEHAVIORAL Food supplementation: nopales
- BEHAVIORAL Food supplementation: cucumber
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2013-01 |
| Est. Completion | 2014-03 |
| Phase | NA |
What the finished NCT02209493 record still lists
NCT02209493 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Food supplementation: nopales is the first listed.
NCT02209493 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02209493 about?
NCT02209493 is a clinical study titled "Effects of Nopales (Opuntia Spp.) on Lipoprotein Profile and Oxidative Stress in Moderately Hypercholesterolemic Adults". In light of the high CVD morbidity and mortality, promoting simple interventions to improve serum lipids and decrease oxidative stress are warranted to help prevent chronic diseases. Because of their fiber content, nopales (prickly pear cactus pads from the Opuntia species) are commonly regarded amo...
What is the current status of trial NCT02209493?
This trial is currently completed. It is a NA study. The enrollment target is 27 participants. The study started on 2013-01. Estimated completion is 2014-03.
What interventions are being tested in trial NCT02209493?
The interventions under investigation include: Food supplementation: nopales (BEHAVIORAL), Food supplementation: cucumber (BEHAVIORAL).
Who is sponsoring clinical trial NCT02209493?
This trial is sponsored by Arizona State University, which has 187 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02209493's enrollment target sits among peer trials
27 1708th of 2000 higher than 291 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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