Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02207777 · ClinicalTrials.gov registry record · NA

Weight Loss-Independent Metabolic Effects of Roux-En-Y Gastric Bypass in Diabetes

A NA study, sponsored by Washington University School of Medicine.

Completed
Registry status
NA
Development phase
65
Enrollment target

NCT02207777: Completed NA study, sponsored by Washington University School of Medicine.

NCT02207777 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 65 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02207777, a NA study, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
NA
Development phase
65 participants
Enrollment target

Study Summary

For this purpose, we will compare the effects of targeted 16-18% (with a range of 16-25%) weight loss induced by Roux-en-Y Gastric bypass (RYGB) surgery with the same weight loss induced by a low-calorie diet (LCD) on liver and skeletal muscle insulin sensitivity, beta-cell function, and 24-hour metabolic homeostasis in obese subjects with or without T2D.

Primary Outcome

The outcome will be assessed by hyperinsulinemic-euglycemic-pancreatic-clamp procedure before and after weight loss.

Interventions

  • PROCEDURE Roux-en-Y gastric bypass surgery
  • BEHAVIORAL Low-calorie diet

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2014-08
Est. Completion 2019-03
Phase NA

What the finished NCT02207777 record still lists

NCT02207777 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Roux-en-Y gastric bypass surgery is the first listed.

NCT02207777 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02207777 about?

NCT02207777 is a clinical study titled "Weight Loss-Independent Metabolic Effects of Roux-En-Y Gastric Bypass in Diabetes". For this purpose, we will compare the effects of targeted 16-18% (with a range of 16-25%) weight loss induced by Roux-en-Y Gastric bypass (RYGB) surgery with the same weight loss induced by a low-calorie diet (LCD) on liver and skeletal muscle insulin sensitivity, beta-cell function, and 24-hour met...

What is the current status of trial NCT02207777?

This trial is currently completed. It is a NA study. The enrollment target is 65 participants. The study started on 2014-08. Estimated completion is 2019-03.

What interventions are being tested in trial NCT02207777?

The interventions under investigation include: Roux-en-Y gastric bypass surgery (PROCEDURE), Low-calorie diet (BEHAVIORAL).

Who is sponsoring clinical trial NCT02207777?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02207777's enrollment target sits among peer trials

65 1144th of 2000 higher than 854 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03366116 · 65 participants · Phase 1

    5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

  • NCT03603730 · 65 participants · NA

    Vagal Nerve Stimulation for Functional Dyspepsia and Gastroparesis

  • NCT03796559 · 65 participants · NA

    Magseed Enabled Long-Term Localization of Axillary Lymph Nodes

  • NCT03993106 · 65 participants · Phase 2

    A Study of sEphB4-HSA in Kaposi Sarcoma

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT02207777, the US trial registry maintained by the National Library of Medicine. NCT02207777 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.