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NCT02204579 · ClinicalTrials.gov registry record · Phase 2

A Study to Determine the Effects of NPSP795 on the Calcium-sensing Receptor in Subjects With Autosomal Dominant Hypocalcemia as Measured by PTH Levels and Blood Calcium Concentrations

A Phase 2 study, sponsored by Shire.

Completed
Registry status
Phase 2
Development phase
7
Enrollment target

NCT02204579 is a Phase 2 study that has completed, run by Shire. The registered enrollment target is 7 participants.

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The verdict

NCT02204579, a Phase 2 study, has completed, sponsored by Shire.

COMPLETED
Registry status
Phase 2
Development phase
7 participants
Enrollment target

Study Summary

This is an open-label study looking at the effects of NPSP795 (a selective calcium receptor antagonist) on activating mutations of the Calcium-sensing receptor in patients with Autosomal Dominant Hypocalcemia. Patients with ADH have low blood calcium levels and an inappropriately increased renal calcium excretion, decreased renal phosphate excretion, and hyperphosphatemia. PTH and blood calcium levels will be tested during and after the IV infusion of NPSP795. Concentrations of NPSP795 and length of time of IV infusion will vary depending on measured levels of ionized calcium.

Interventions

  • DRUG NPSP795

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2014-07-18
Est. Completion 2015-05-04
Phase Phase 2

Sponsor

Shire

245 total trials

What the Registry Record Tells You About NCT02204579

The ClinicalTrials.gov registry entry for NCT02204579 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shire, which has 245 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which NPSP795 is the first listed.

NCT02204579 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02204579 about?

NCT02204579 is a clinical study titled "A Study to Determine the Effects of NPSP795 on the Calcium-sensing Receptor in Subjects With Autosomal Dominant Hypocalcemia as Measured by PTH Levels and Blood Calcium Concentrations". This is an open-label study looking at the effects of NPSP795 (a selective calcium receptor antagonist) on activating mutations of the Calcium-sensing receptor in patients with Autosomal Dominant Hypocalcemia. Patients with ADH have low blood calcium levels and an inappropriately increased renal cal...

What is the current status of trial NCT02204579?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 7 participants. The study started on 2014-07-18. Estimated completion is 2015-05-04.

What interventions are being tested in trial NCT02204579?

The interventions under investigation include: NPSP795 (DRUG).

Who is sponsoring clinical trial NCT02204579?

This trial is sponsored by Shire, which has 245 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.