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NCT02200770 · ClinicalTrials.gov registry record · Phase 2

N-MOmentum: A Clinical Research Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorders

A Phase 2 study, sponsored by MedImmune.

Completed
Registry status
Phase 2
Development phase
231
Enrollment target

NCT02200770: Completed Phase 2 study, sponsored by MedImmune.

NCT02200770 is a Phase 2 study that has completed, run by MedImmune. The registered enrollment target is 231 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02200770, a Phase 2 study, has completed, sponsored by MedImmune.

COMPLETED
Registry status
Phase 2
Development phase
231 participants
Enrollment target

Study Summary

To compare the efficacy of inebilizumab (MEDI-551) versus placebo in reducing the risk of an neuromyelitis optica/neuromyelitis optica- spectrum disorders (NMO/NMOSD) attack in participants with NMO/NMOSD.

Primary Outcome

The NMOSD attack is defined as the presence of new or worsening symptom(s) related to NMOSD that meet at least one of the 18 protocol-defined attack criteria. These criteria were developed in conjunction with a panel of disease experts and with Food and Drug Administration input, and were intended to be clinically meaningful, objective, quantifiable, and able to be used worldwide. Only attacks positively adjudicated by the AC were used for the primary analysis.

Interventions

  • OTHER Placebo
  • DRUG Inebilizumab

Trial Details

FieldValue
Enrollment Target 231 participants
Start Date 2015-04-01
Est. Completion 2020-11-06
Phase Phase 2
MedImmune

210 total trials

What the finished NCT02200770 record still lists

NCT02200770 is an interventional study that assigns participants to a tested intervention. The registered 231 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02200770 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02200770 about?

NCT02200770 is a clinical study titled "N-MOmentum: A Clinical Research Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorders". To compare the efficacy of inebilizumab (MEDI-551) versus placebo in reducing the risk of an neuromyelitis optica/neuromyelitis optica- spectrum disorders (NMO/NMOSD) attack in participants with NMO/NMOSD.

What is the current status of trial NCT02200770?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 231 participants. The study started on 2015-04-01. Estimated completion is 2020-11-06.

What interventions are being tested in trial NCT02200770?

The interventions under investigation include: Placebo (OTHER), Inebilizumab (DRUG).

Who is sponsoring clinical trial NCT02200770?

This trial is sponsored by MedImmune, which has 210 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02200770's enrollment target sits among peer trials

231 257th of 2000 higher than 1,744 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02200770, the US trial registry maintained by the National Library of Medicine. NCT02200770 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.