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NCT02195895 · ClinicalTrials.gov registry record · Phase 2
Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury (SCI) Previously Treated With Teriparatide
A Phase 2 study, sponsored by Northwestern University.
- Completed
- Registry status
- Phase 2
- Development phase
- 17
- Enrollment target
NCT02195895: Completed Phase 2 study, sponsored by Northwestern University.
NCT02195895 is a Phase 2 study that has completed, run by Northwestern University. The registered enrollment target is 17 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02195895, a Phase 2 study, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 17 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if a year of alendronate treatment will maintain or increase bone mass density (BMD) compared to baseline BMD values in people with chronic spinal cord injury (SCI). This study will also investigate 1) if alendronate therapy will increase bone strength in people with chronic SCI, 2) the number of participants with adverse events from alendronate, and 3) the effects of alendronate on serum markers of bone metabolism.
Primary Outcome
The mean percent change in bone mineral density (BMD) of the hip after 12 months of treatment. BMD was evaluated by dual-energy X-ray absorptiometry (DXA). DXA scans measure bone density in different areas of the body using low-dose X-ray beams.
Interventions
- DIETARY_SUPPLEMENT Vitamin D
- DRUG Alendronate
- DIETARY_SUPPLEMENT Calcium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2014-04 |
| Est. Completion | 2016-08-05 |
| Phase | Phase 2 |
What the finished NCT02195895 record still lists
NCT02195895 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 3 interventions - of which Vitamin D is the first listed.
NCT02195895 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02195895 about?
NCT02195895 is a clinical study titled "Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury (SCI) Previously Treated With Teriparatide". The purpose of this study is to determine if a year of alendronate treatment will maintain or increase bone mass density (BMD) compared to baseline BMD values in people with chronic spinal cord injury (SCI). This study will also investigate 1) if alendronate therapy will increase bone strength in p...
What is the current status of trial NCT02195895?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 17 participants. The study started on 2014-04. Estimated completion is 2016-08-05.
What interventions are being tested in trial NCT02195895?
The interventions under investigation include: Vitamin D (DIETARY_SUPPLEMENT), Alendronate (DRUG), Calcium (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02195895?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02195895's enrollment target sits among peer trials
17 1903rd of 2000 higher than 93 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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