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NCT02189785 · ClinicalTrials.gov registry record
Endogenous Opioid Mechanisms for Rejection Sensitivity
A clinical trial, sponsored by Stony Brook University.
- Completed
- Registry status
- 114
- Enrollment target
NCT02189785: Completed study, sponsored by Stony Brook University.
NCT02189785 is a clinical trial that has completed, run by Stony Brook University. The registered enrollment target is 114 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02189785 has completed, sponsored by Stony Brook University.
- COMPLETED
- Registry status
- 114 participants
- Enrollment target
Study Summary
This project hypothesizes that the brain's opioid system determines rejection sensitivity, a personality trait that is a vulnerability factor and feature of several psychiatric disorders. This project will use positron emission tomography to measure the brain's opioid response to social rejection and acceptance in a nonclinical population with varying levels of rejection sensitivity. The results will provide the first major step towards understanding a neurotransmitter mechanism for rejection sensitivity, allowing for further investigation into predicting and treating its associated disorders.
Primary Outcome
This study will measure levels of radiotracer (carbon-11-labeled carfentanil) binding to the mu-opioid receptor in the brain using positron-emission tomography (PET). Primary regions of interest include: the amygdala, anterior insular cortex, anterior cingulate cortex, nucleus accumbens, and thalamus. All structures will be examined bilaterally. Differences in binding potential (Bmax/Kd) for the radiotracer will be compared across different experimental conditions (e.g., neutral, positive, negat
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 114 participants |
| Start Date | 2016-08 |
| Est. Completion | 2019-06-06 |
What the finished NCT02189785 record still lists
NCT02189785 is an observational study that tracks outcomes without assigning an intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT02189785 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02189785 about?
NCT02189785 is a clinical study titled "Endogenous Opioid Mechanisms for Rejection Sensitivity". This project hypothesizes that the brain's opioid system determines rejection sensitivity, a personality trait that is a vulnerability factor and feature of several psychiatric disorders. This project will use positron emission tomography to measure the brain's opioid response to social rejection an...
What is the current status of trial NCT02189785?
This trial is currently completed. The enrollment target is 114 participants. The study started on 2016-08. Estimated completion is 2019-06-06.
Who is sponsoring clinical trial NCT02189785?
This trial is sponsored by Stony Brook University, which has 127 total clinical trials registered on ClinicalTrials.gov.
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