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NCT02185144 · ClinicalTrials.gov registry record · NA

PATH For Triples Study: Medication and Lifestyle Adherence for HIV+ Patients

A NA study, sponsored by University of Pennsylvania.

Completed
Registry status
NA
Development phase
129
Enrollment target

NCT02185144: Completed NA study, sponsored by University of Pennsylvania.

NCT02185144 is a NA study that has completed, run by University of Pennsylvania. The registered enrollment target is 129 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02185144, a NA study, has completed, sponsored by University of Pennsylvania.

COMPLETED
Registry status
NA
Development phase
129 participants
Enrollment target

Study Summary

The PATH for Triples (PFT) Study is an effectiveness trial comparing a nurse health navigator (NHN) model for HIV+ persons with severe mental illness and substance abuse (i.e., triply diagnosed) with Treatment as Usual (TAU). The team completed a Phase II trial of the nurse health navigator model for HIV+ persons with severe mental illness that showed the intervention was effective. The investigators are now testing the intervention in a real world setting with patients recruited from psychiatric and substance abuse inpatient units in Philadelphia using a longitudinal design. The intervention is set up as a cascade where non-adherent patients receive additional visits from the study nurses. It is hypothesized that patients assigned to the NHN will have better medication compliance, reduced viral loads and improved CD4 counts compared to patients assigned to TAU. It is also hypothesized that the PFT intervention group will be more cost effective compared to TAU. This group of triply diagnosed patients are at very high risk of negative health outcomes and secondary transmission of HIV and, therefore, the study is of high public health significance.

Primary Outcome

Change in viral load based on collection of blood specimens at baseline, 3, 6 and 9 months

Interventions

  • BEHAVIORAL Treatment as Usual
  • BEHAVIORAL PATH For Triples

Trial Details

FieldValue
Enrollment Target 129 participants
Start Date 2014-02
Est. Completion 2019-08
Phase NA
University of Pennsylvania

1,423 total trials

What the finished NCT02185144 record still lists

NCT02185144 is an interventional study that assigns participants to a tested intervention. The registered 129 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 2 interventions - of which Treatment as Usual is the first listed.

NCT02185144 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02185144 about?

NCT02185144 is a clinical study titled "PATH For Triples Study: Medication and Lifestyle Adherence for HIV+ Patients". The PATH for Triples (PFT) Study is an effectiveness trial comparing a nurse health navigator (NHN) model for HIV+ persons with severe mental illness and substance abuse (i.e., triply diagnosed) with Treatment as Usual (TAU). The team completed a Phase II trial of the nurse health navigator model fo...

What is the current status of trial NCT02185144?

This trial is currently completed. It is a NA study. The enrollment target is 129 participants. The study started on 2014-02. Estimated completion is 2019-08.

What interventions are being tested in trial NCT02185144?

The interventions under investigation include: Treatment as Usual (BEHAVIORAL), PATH For Triples (BEHAVIORAL).

Who is sponsoring clinical trial NCT02185144?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02185144's enrollment target sits among peer trials

129 744th of 2000 higher than 1,257 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02185144, the US trial registry maintained by the National Library of Medicine. NCT02185144 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.