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NCT02162719 · ClinicalTrials.gov registry record · Phase 2

A Study Assessing the Safety and Efficacy of Adding Ipatasertib to Paclitaxel Treatment in Participants With Breast Cancer That Has Spread Beyond the Initial Site, and the Cancer Does Not Have Certain Hormonal Receptors

A Phase 2 study, sponsored by Genentech.

Completed
Registry status
Phase 2
Development phase
124
Enrollment target

NCT02162719 is a Phase 2 study that has completed, run by Genentech. The registered enrollment target is 124 participants.

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The verdict

NCT02162719, a Phase 2 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 2
Development phase
124 participants
Enrollment target

Study Summary

This multicenter, randomized, double-blind study will estimate the efficacy, safety and tolerability of ipatasertib combined with paclitaxel compared with placebo combined with paclitaxel in participants with inoperable locally advanced or metastatic triple-negative breast cancer (mTNBC), as measured by progression-free survival (PFS) in all participants and in participants with phosphatase and tensin homolog (PTEN)-low tumors.

Interventions

  • DRUG Placebo
  • DRUG Ipatasertib
  • DRUG Paclitaxel

Trial Details

FieldValue
Enrollment Target 124 participants
Start Date 2014-08-19
Est. Completion 2019-08-31
Phase Phase 2

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT02162719

The ClinicalTrials.gov registry entry for NCT02162719 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 124 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02162719 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02162719 about?

NCT02162719 is a clinical study titled "A Study Assessing the Safety and Efficacy of Adding Ipatasertib to Paclitaxel Treatment in Participants With Breast Cancer That Has Spread Beyond the Initial Site, and the Cancer Does Not Have Certain Hormonal Receptors". This multicenter, randomized, double-blind study will estimate the efficacy, safety and tolerability of ipatasertib combined with paclitaxel compared with placebo combined with paclitaxel in participants with inoperable locally advanced or metastatic triple-negative breast cancer (mTNBC), as measure...

What is the current status of trial NCT02162719?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 124 participants. The study started on 2014-08-19. Estimated completion is 2019-08-31.

What interventions are being tested in trial NCT02162719?

The interventions under investigation include: Placebo (DRUG), Ipatasertib (DRUG), Paclitaxel (DRUG).

Who is sponsoring clinical trial NCT02162719?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.