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NCT02157974 · ClinicalTrials.gov registry record · Phase 2
Liver and Fat Regulation in Overweight Adolescent Girls
A Phase 2 study, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- Phase 2
- Development phase
- 92
- Enrollment target
NCT02157974: Completed Phase 2 study, sponsored by University of Colorado, Denver.
NCT02157974 is a Phase 2 study that has completed, run by University of Colorado, Denver. The registered enrollment target is 92 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (31% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02157974, a Phase 2 study, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 92 participants
- Enrollment target
Study Summary
Women with polycystic ovarian syndrome (PCOS) have increased rates of hepatic steatosis compared to weight similar women with regular menses. It is unclear if this is related to high testosterone or insulin resistance. The investigators will assess hepatic glucose release, rates of lipolysis and hepatic de novo lipogenesis in the fasted and postprandial state to determine if alterations in the processes contribute to hepatic steatosis. Participants will be overweight, sedentary girls with or without PCOS. Those with PCOS will either be medication naive, or must be taking metformin or combined oral contraceptives (COCPs) for a period of at least 6 months prior to study procedures.
Primary Outcome
Hepatic glucose release will be measured by the rate of appearance of a glucose tracer. Glucose rate of appearance reflects the amount of glucose being release by primarily the liver during fasting. A higher glucose rate of appearance is often seen with dysglycemia
Interventions
- DRUG Byetta 5Mcg Pen Injection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 92 participants |
| Start Date | 2014-08 |
| Est. Completion | 2022-12 |
| Phase | Phase 2 |
What the finished NCT02157974 record still lists
NCT02157974 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 92 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (31% lower).
The record links to 0 conditions, and to 1 intervention - of which Byetta 5Mcg Pen Injection is the first listed.
NCT02157974 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02157974 about?
NCT02157974 is a clinical study titled "Liver and Fat Regulation in Overweight Adolescent Girls". Women with polycystic ovarian syndrome (PCOS) have increased rates of hepatic steatosis compared to weight similar women with regular menses. It is unclear if this is related to high testosterone or insulin resistance. The investigators will assess hepatic glucose release, rates of lipolysis and hep...
What is the current status of trial NCT02157974?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 92 participants. The study started on 2014-08. Estimated completion is 2022-12.
What interventions are being tested in trial NCT02157974?
The interventions under investigation include: Byetta 5Mcg Pen Injection (DRUG).
Who is sponsoring clinical trial NCT02157974?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02157974's enrollment target sits among peer trials
92 767th of 2000 higher than 1,230 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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