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NCT02155699 · ClinicalTrials.gov registry record · NA
Exercise and Markers of Medial Temporal Health in Youth At-risk for Psychosis
A NA study of Attenuated Psychosis Syndrome, sponsored by University of Colorado, Boulder.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT02155699: Completed NA study of Attenuated Psychosis Syndrome, sponsored by University of Colorado, Boulder.
NCT02155699 is a NA study of Attenuated Psychosis Syndrome that has completed, run by University of Colorado, Boulder. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02155699, a NA study of Attenuated Psychosis Syndrome, has completed, sponsored by University of Colorado, Boulder.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this proposal is to test the feasibility and effectiveness of cardiovascular exercise in promoting brain health and improving related symptoms (e.g., hearing sounds that are not there, feeling emotionally detached from self and others), cognitive difficulties (troubles with memory and learning), and every day social-occupational functioning in youth at imminent risk for developing a psychotic disorder such as schizophrenia. Understanding how exercise may protect or improve the health of a brain area that is implicated as a major contributing factor to the onset of psychosis may lead to a path-breaking new intervention that does not suffer from many of the side effects, costs, and other barriers that characterize treatments that are currently available for this group. Because a significant portion of high-risk youth go on to develop a psychotic disorder in a short period, intervening at this stage may help to improve the clinical course and ultimately prevent the onset of a devastating and prevalent mental illness.
Primary Outcome
Medial temporal structures (hippocampus and parahippocampal gyrus) will be delineated automatically using the FMRIB's Integrated Registration and Segmentation Tool algorithm within the FMRIB's Software Library (FSL) image-processing suite. Secondly, the structures will be evaluated with vertex analyses (assessing changes in shape post trial on a per-vertex basis), which will also be carried out utilizing FIRST. Shape/appearance models used in FIRST are constructed from manually segmented images
Conditions Studied
Interventions
- BEHAVIORAL Exercise 1
- BEHAVIORAL Exercise 2
Study Locations (1)
Colorado
- ADAPT Program - Boulder
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2014-07 |
| Est. Completion | 2022-07 |
| Phase | NA |
What the finished NCT02155699 record still lists
NCT02155699 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Attenuated Psychosis Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Exercise 1 is the first listed.
NCT02155699 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT02155699 about?
NCT02155699 is a clinical study titled "Exercise and Markers of Medial Temporal Health in Youth At-risk for Psychosis". The goal of this proposal is to test the feasibility and effectiveness of cardiovascular exercise in promoting brain health and improving related symptoms (e.g., hearing sounds that are not there, feeling emotionally detached from self and others), cognitive difficulties (troubles with memory and le...
What is the current status of trial NCT02155699?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2014-07. Estimated completion is 2022-07.
What conditions does trial NCT02155699 study?
This clinical trial studies the following conditions: Attenuated Psychosis Syndrome.
What interventions are being tested in trial NCT02155699?
The interventions under investigation include: Exercise 1 (BEHAVIORAL), Exercise 2 (BEHAVIORAL).
Who is sponsoring clinical trial NCT02155699?
This trial is sponsored by University of Colorado, Boulder, which has 69 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02155699 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02155699's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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